A Triumvirate:: Correlating Thyroid Cytopathology, Molecular Testing, and Histopathology.
Surg Pathol Clin
; 16(1): 1-14, 2023 Mar.
Article
de En
| MEDLINE
| ID: mdl-36739157
ABSTRACT
Risk stratification is essential in the preoperative evaluation and management of thyroid nodules, most of which are benign. Advances in DNA and RNA sequencing have shed light on the molecular drivers of thyroid cancer. Molecular testing of cytologically indeterminate nodules has helped refine risk stratification, triage patients for surgery, and determine the extent of surgery. Molecular platforms with high negative predictive values can help identify nodules that may be spared surgery and can be managed conservatively. Here we discuss the importance of integrating cytomorphologic, molecular, and histologic features to help avoid errors and improve patient management.
Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Tumeurs de la thyroïde
/
Nodule thyroïdien
Type d'étude:
Diagnostic_studies
/
Prognostic_studies
Limites:
Humans
Langue:
En
Journal:
Surg Pathol Clin
Année:
2023
Type de document:
Article