Alleviation of arthritis through prevention of neutrophil extracellular traps by an orally available inhibitor of protein arginine deiminase 4.

Gajendran, Chandru; Fukui, Shoichi; Sadhu, Naveen M; Zainuddin, Mohammed; Rajagopal, Sridharan; Gosu, Ramachandraiah; Gutch, Sarah; Fukui, Saeko; Sheehy, Casey E; Chu, Long; Vishwakarma, Santosh; Jeyaraj, D A; Hallur, Gurulingappa; Wagner, Denisa D; Sivanandhan, Dhanalakshmi

Gajendran, Chandru; Fukui, Shoichi; Sadhu, Naveen M; Zainuddin, Mohammed; Rajagopal, Sridharan; Gosu, Ramachandraiah; Gutch, Sarah; Fukui, Saeko; Sheehy, Casey E; Chu, Long; Vishwakarma, Santosh; Jeyaraj, D A; Hallur, Gurulingappa; Wagner, Denisa D; Sivanandhan, Dhanalakshmi.

Affiliation

Gajendran C; Jubilant Therapeutics Inc., Bedminster, NJ, USA.
Fukui S; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, 02115, USA.
Sadhu NM; Department of Pediatrics, Harvard Medical School, Boston, MA, 02115, USA.
Zainuddin M; Jubilant Therapeutics Inc., Bedminster, NJ, USA.
Rajagopal S; Jubilant Therapeutics Inc., Bedminster, NJ, USA.
Gosu R; Jubilant Therapeutics Inc., Bedminster, NJ, USA.
Gutch S; Jubilant Therapeutics Inc., Bedminster, NJ, USA.
Fukui S; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, 02115, USA.
Sheehy CE; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, 02115, USA.
Chu L; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, 02115, USA.
Vishwakarma S; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, 02115, USA.
Jeyaraj DA; Jubilant Biosys Limited, Bangalore, India.
Hallur G; Jubilant Biosys Limited, Bangalore, India.
Wagner DD; Jubilant Biosys Limited, Bangalore, India.
Sivanandhan D; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, 02115, USA.

Sci Rep ; 13(1): 3189, 2023 02 23.

Article de En | MEDLINE | ID: mdl-36823444

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Polyarthrite rhumatoïde / Pièges extracellulaires / Protein-arginine deiminase Type 4 Limites: Animals / Humans Langue: En Journal: Sci Rep Année: 2023 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: Royaume-Uni

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