Design and synthesis of novel cytotoxic fluoroquinolone analogs through topoisomerase inhibition, cell cycle arrest, and apoptosis.

Elanany, Mohamed A; Osman, Essam Eldin A; Gedawy, Ehab Mohamed; Abou-Seri, Sahar M

Elanany, Mohamed A; Osman, Essam Eldin A; Gedawy, Ehab Mohamed; Abou-Seri, Sahar M.

Affiliation

Elanany MA; Department of Pharmaceutical Chemistry, School of Pharmacy and Pharmaceutical Industries, Badr University in Cairo (BUC), Badr City, 11829, Cairo, Egypt. mohamed.elanany@buc.edu.eg.
Osman EEA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt.
Gedawy EM; Department of Pharmaceutical Chemistry, School of Pharmacy and Pharmaceutical Industries, Badr University in Cairo (BUC), Badr City, 11829, Cairo, Egypt.
Abou-Seri SM; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt.

Sci Rep ; 13(1): 4144, 2023 03 13.

Article de En | MEDLINE | ID: mdl-36914702

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Fluoroquinolones / Antinéoplasiques Limites: Humans Langue: En Journal: Sci Rep Année: 2023 Type de document: Article Pays d'affiliation: Égypte

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