Pseudotyped Virus for Flaviviridae.
Adv Exp Med Biol
; 1407: 313-327, 2023.
Article
de En
| MEDLINE
| ID: mdl-36920705
ABSTRACT
Members of Flaviviridae are enveloped single positive-stranded RNA viruses including hepacivirus, pestivirus, pegivirus, and mosquito-transmitted flavivirus, which are important pathogens of infectious diseases and pose serious threats to human health. Pseudotyped virus is an artificially constructed virus-like particle, which could infect host cells similar to a live virus but cannot produce infectious progeny virus. Therefore, pseudotyped virus has the advantages of a wide host range, high transfection efficiency, low biosafety risk, and accurate and objective quantification. It has been widely used in biological characteristics, drug screening, detection methods, and vaccine evaluation of Flaviviridae viruses like hepatitis C virus, Japanese encephalitis virus, dengue virus, and Zika virus.
Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Flaviviridae
/
Flavivirus
/
Virus Zika
/
Infection par le virus Zika
Limites:
Animals
/
Humans
Langue:
En
Journal:
Adv Exp Med Biol
Année:
2023
Type de document:
Article
Pays d'affiliation:
Chine