Overexpression screen of chromosome 21 genes reveals modulators of Sonic hedgehog signaling relevant to Down syndrome.

Moyer, Anna J; Fernandez, Fabian-Xosé; Li, Yicong; Klinedinst, Donna K; Florea, Liliana D; Kazuki, Yasuhiro; Oshimura, Mitsuo; Reeves, Roger H

Moyer, Anna J; Fernandez, Fabian-Xosé; Li, Yicong; Klinedinst, Donna K; Florea, Liliana D; Kazuki, Yasuhiro; Oshimura, Mitsuo; Reeves, Roger H.

Affiliation

Moyer AJ; Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Fernandez FX; Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Li Y; Department of Neurobiology, University of Alabama at Birmingham, Birmingham, AL 35233, USA.
Klinedinst DK; Department of Psychology, University of Arizona, Tucson, AZ 85724, USA.
Florea LD; Department of Neurology, University of Arizona, Tucson, AZ 85724, USA.
Kazuki Y; BIO5 and McKnight Brain Research Institutes, Tucson, AZ 85721, USA.
Oshimura M; Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Reeves RH; Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

Dis Model Mech ; 16(4)2023 04 01.

Article de En | MEDLINE | ID: mdl-36995257

Sujet(s)
Mots clés

Aneuploidy; Down syndrome; Gene dosage effects; Genetic screen; Sonic hedgehog; Trisomy 21

Texte intégral

Ajouter à My VHL

Imprimer

XML

PubMed Links

Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Syndrome de Down / Protéine HMGN1 Type d'étude: Prognostic_studies Limites: Animals / Humans Langue: En Journal: Dis Model Mech Sujet du journal: MEDICINA Année: 2023 Type de document: Article Pays d'affiliation: États-Unis d'Amérique

Texte intégral

Ajouter à My VHL

Imprimer

XML

PubMed Links

Recherche sur Google