Synthesis of the first remdesivir cocrystal: design, characterization, and therapeutic potential for pulmonary delivery.

Wong, Si Nga; Low, Kam-Hung; Poon, Yi Lam; Zhang, Xinyue; Chan, Ho Wan; Chow, Shing Fung

Wong, Si Nga; Low, Kam-Hung; Poon, Yi Lam; Zhang, Xinyue; Chan, Ho Wan; Chow, Shing Fung.

Affiliation

Wong SN; Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
Low KH; Department of Chemistry, Faculty of Science, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
Poon YL; Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
Zhang X; Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
Chan HW; Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
Chow SF; Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China; Advanced Biomedical Instrumentation Centre, Hong Kong Science Park, Shatin, Hong Kong SAR, China. Electronic address: asfchow@hku.hk.

Int J Pharm ; 640: 122983, 2023 Jun 10.

Article de En | MEDLINE | ID: mdl-37121494

Sujet(s)
Mots clés

Cocrystal; Dry powder inhaler; Pulmonary drug delivery; Remdesivir; Spray drying

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Chimie pharmaceutique / COVID-19 Limites: Humans Langue: En Journal: Int J Pharm Année: 2023 Type de document: Article Pays d'affiliation: Chine Pays de publication: Pays-Bas

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