CYP2C19 loss-of-function alleles are not associated with higher prevalence of gastrointestinal bleeds in those who have been prescribed antidepressants: Analysis in a British-South Asian cohort.

Magavern, Emma F; van Heel, David A; Smedley, Damian; Caulfield, Mark J

Magavern, Emma F; van Heel, David A; Smedley, Damian; Caulfield, Mark J.

Affiliation

Magavern EF; William Harvey Research Institute, Queen Mary University of London, London, UK.
van Heel DA; Blizard Institute, Queen Mary University of London, London, UK.
Smedley D; William Harvey Research Institute, Queen Mary University of London, London, UK.
Caulfield MJ; William Harvey Research Institute, Queen Mary University of London, London, UK.

Br J Clin Pharmacol ; 89(11): 3432-3438, 2023 11.

Article de En | MEDLINE | ID: mdl-37143396

Sujet(s)
Mots clés

antidepressants; cytochrome P450 enzymes; pharmacogenomics; pharmacotherapy

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Cytochrome P-450 CYP2C19 / Hémorragie gastro-intestinale / Antidépresseurs Type d'étude: Prevalence_studies / Risk_factors_studies Limites: Humans Pays/Région comme sujet: Asia / Europa Langue: En Journal: Br J Clin Pharmacol Année: 2023 Type de document: Article Pays de publication: Royaume-Uni

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