Comparative Pharmacokinetics of Scoparone and its Metabolite Scopoletin in Normal and ANIT-induced Intrahepatic Cholestatic Rats.

Tian, Qiru; Jin, Huan; Huo, Xiaokui; Zhao, Yupu; Wu, Wenhui; Xu, Lei; Wang, Yinan; Yang, Xiaobo; Sun, Chengpeng; Deng, Sa; Shu, Xiaohong

Tian, Qiru; Jin, Huan; Huo, Xiaokui; Zhao, Yupu; Wu, Wenhui; Xu, Lei; Wang, Yinan; Yang, Xiaobo; Sun, Chengpeng; Deng, Sa; Shu, Xiaohong.

Affiliation

Tian Q; College of Pharmacy, Dalian Medical University, Dalian, 116044, China.
Jin H; Hainan Vocational University of Science and Technology, Haikou, 571126, China.
Huo X; College of Pharmacy, Dalian Medical University, Dalian, 116044, China.
Zhao Y; College of Pharmacy, Dalian Medical University, Dalian, 116044, China.
Wu W; College of Pharmacy, Dalian Medical University, Dalian, 116044, China.
Xu L; College of Pharmacy, Dalian Medical University, Dalian, 116044, China.
Wang Y; College of Pharmacy, Dalian Medical University, Dalian, 116044, China.
Yang X; College of Pharmacy, Dalian Medical University, Dalian, 116044, China.
Sun C; College of Pharmacy, Dalian Medical University, Dalian, 116044, China.
Deng S; College of Pharmacy, Dalian Medical University, Dalian, 116044, China.
Shu X; College of Pharmacy, Dalian Medical University, Dalian, 116044, China.

Curr Drug Metab ; 24(4): 303-311, 2023.

Article de En | MEDLINE | ID: mdl-37165497

Sujet(s)
Mots clés

LC-MS/MS; Scoparone; cholestasis; comparative; pharmacokinetics; scopoletin

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Scopolétine / Cholestase Limites: Animals Langue: En Journal: Curr Drug Metab Sujet du journal: METABOLISMO / QUIMICA Année: 2023 Type de document: Article Pays d'affiliation: Chine Pays de publication: Pays-Bas

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