Generation of a homozygous GRIN2A gene knockout human embryonic stem cell line using CRISPR/Cas9 system.

Luo, Xian; Yang, Kaiming; Jiang, Meiling; Chen, Tao; Chi, Yue; Ma, Bingxiu; Lai, Liangxue; Zou, Qingjian

Luo, Xian; Yang, Kaiming; Jiang, Meiling; Chen, Tao; Chi, Yue; Ma, Bingxiu; Lai, Liangxue; Zou, Qingjian.

Affiliation

Luo X; Guangdong Provincial Key Laboratory of Large Animal Models for Biomedicine, South China Institute of Large Animal Models for Biomedicine, School of Biotechnology and Health Science, Wuyi University, Jiangmen, China.
Yang K; CAS Key Laboratory of Regenerative Biology, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China; GMU-GIBH Joint School of Life Sciences, Guangzhou Medical University, China.
Jiang M; Guangdong Provincial Key Laboratory of Large Animal Models for Biomedicine, South China Institute of Large Animal Models for Biomedicine, School of Biotechnology and Health Science, Wuyi University, Jiangmen, China.
Chen T; Guangdong Provincial Key Laboratory of Large Animal Models for Biomedicine, South China Institute of Large Animal Models for Biomedicine, School of Biotechnology and Health Science, Wuyi University, Jiangmen, China.
Chi Y; Guangdong Provincial Key Laboratory of Large Animal Models for Biomedicine, South China Institute of Large Animal Models for Biomedicine, School of Biotechnology and Health Science, Wuyi University, Jiangmen, China.
Ma B; Department of Gynecology and Obstetrics, Key Laboratory for Major Obstetric Diseases of Guangdong Province, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou 510150, China. Electronic address: bxma@stu.gzhmu.edu.cn.
Lai L; Guangdong Provincial Key Laboratory of Large Animal Models for Biomedicine, South China Institute of Large Animal Models for Biomedicine, School of Biotechnology and Health Science, Wuyi University, Jiangmen, China; CAS Key Laboratory of Regenerative Biology, Guangzhou Institutes of Biomedicine and
Zou Q; Guangdong Provincial Key Laboratory of Large Animal Models for Biomedicine, South China Institute of Large Animal Models for Biomedicine, School of Biotechnology and Health Science, Wuyi University, Jiangmen, China. Electronic address: wyuchemzqj@126.com.

Stem Cell Res ; 69: 103121, 2023 06.

Article de En | MEDLINE | ID: mdl-37182381

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Systèmes CRISPR-Cas / Cellules souches embryonnaires humaines Limites: Humans Langue: En Journal: Stem Cell Res Année: 2023 Type de document: Article Pays d'affiliation: Chine

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