Emergence of hybrid airway neutrophils with increased mitochondrial metabolism and low inflammatory response in neutrophilic asthma: evidence supporting targeting inhibition of neutrophil glycolysis in this asthma sub-group.

Yang, Y; Li, H; Liu, P; Zhang, X; Wang, Q; Li, H; Cui, N; Tian, X; Long, Y; He, H; Su, L

Yang, Y; Li, H; Liu, P; Zhang, X; Wang, Q; Li, H; Cui, N; Tian, X; Long, Y; He, H; Su, L.

Affiliation

Yang Y; Department of Critical Care Medicine, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing 100730, China.
Li H; School of Medicine, Tsinghua University, Beijing 100084, China.
Liu P; Medical Research Center, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.
Zhang X; School of Medicine, Tsinghua University, Beijing 100084, China.
Wang Q; Department of Critical Care Medicine, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing 100730, China.
Li H; 4+4 Medical Doctor Program, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.
Cui N; Department of Critical Care Medicine, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing 100730, China.
Tian X; Department of Respiratory and Critical Care Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
Long Y; Department of Critical Care Medicine, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing 100730, China.
He H; Department of Critical Care Medicine, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing 100730, China.
Su L; Department of Critical Care Medicine, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing 100730, China.

QJM ; 116(8): 702-704, 2023 09 12.

Article de En | MEDLINE | ID: mdl-37184923

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Asthme / Granulocytes neutrophiles Limites: Humans Langue: En Journal: QJM Sujet du journal: MEDICINA Année: 2023 Type de document: Article Pays d'affiliation: Chine

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