Nanoparticle-mediated genome editing in single-cell embryos via peptide nucleic acids.

Putman, Rachael; Ricciardi, Adele S; Carufe, Kelly E W; Quijano, Elias; Bahal, Raman; Glazer, Peter M; Saltzman, W Mark

Putman, Rachael; Ricciardi, Adele S; Carufe, Kelly E W; Quijano, Elias; Bahal, Raman; Glazer, Peter M; Saltzman, W Mark.

Affiliation

Putman R; Department of Biomedical Engineering Yale University New Haven Connecticut USA.
Ricciardi AS; Department of Therapeutic Radiology Yale University New Haven Connecticut USA.
Carufe KEW; Duke University School of Medicine Durham North Carolina USA.
Quijano E; Department of Biomedical Engineering Yale University New Haven Connecticut USA.
Bahal R; Department of Therapeutic Radiology Yale University New Haven Connecticut USA.
Glazer PM; Department of Surgery University of Pennsylvania Health Systems Philadelphia Pennsylvania USA.
Saltzman WM; Department of Therapeutic Radiology Yale University New Haven Connecticut USA.

Bioeng Transl Med ; 8(3): e10458, 2023 May.

Article de En | MEDLINE | ID: mdl-37206203

Mots clés

PNA; embryo editing; gene editing; nanoparticles; nucleic acid chemistry; peptide nucleic acids; prenatal gene therapy

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Langue: En Journal: Bioeng Transl Med Année: 2023 Type de document: Article