Your browser doesn't support javascript.
loading
The wheat stem rust resistance gene Sr43 encodes an unusual protein kinase.
Yu, Guotai; Matny, Oadi; Gourdoupis, Spyridon; Rayapuram, Naganand; Aljedaani, Fatimah R; Wang, Yan L; Nürnberger, Thorsten; Johnson, Ryan; Crean, Emma E; Saur, Isabel M-L; Gardener, Catherine; Yue, Yajuan; Kangara, Ngonidzashe; Steuernagel, Burkhard; Hayta, Sadiye; Smedley, Mark; Harwood, Wendy; Patpour, Mehran; Wu, Shuangye; Poland, Jesse; Jones, Jonathan D G; Reuber, T Lynne; Ronen, Moshe; Sharon, Amir; Rouse, Matthew N; Xu, Steven; Holusová, Katerina; Bartos, Jan; Molnár, István; Karafiátová, Miroslava; Hirt, Heribert; Blilou, Ikram; Jaremko, Lukasz; Dolezel, Jaroslav; Steffenson, Brian J; Wulff, Brande B H.
Affiliation
  • Yu G; Plant Science Program, Biological and Environmental Science and Engineering Division (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia.
  • Matny O; Center for Desert Agriculture, KAUST, Thuwal, Saudi Arabia.
  • Gourdoupis S; John Innes Centre, Norwich Research Park, Norwich, UK.
  • Rayapuram N; Department of Plant Pathology, University of Minnesota, St. Paul, MN, USA.
  • Aljedaani FR; Bioscience Program, Smart Health Initiative, BESE, KAUST, Thuwal, Saudi Arabia.
  • Wang YL; Plant Science Program, Biological and Environmental Science and Engineering Division (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia.
  • Nürnberger T; Center for Desert Agriculture, KAUST, Thuwal, Saudi Arabia.
  • Johnson R; Plant Science Program, Biological and Environmental Science and Engineering Division (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia.
  • Crean EE; Center for Desert Agriculture, KAUST, Thuwal, Saudi Arabia.
  • Saur IM; Department of Plant Biochemistry, Centre of Plant Molecular Biology (ZMBP), University of Tübingen, Tübingen, Germany.
  • Gardener C; Department of Plant Biochemistry, Centre of Plant Molecular Biology (ZMBP), University of Tübingen, Tübingen, Germany.
  • Yue Y; Department of Plant Pathology, University of Minnesota, St. Paul, MN, USA.
  • Kangara N; Institute for Plant Sciences, University of Cologne, Cologne, Germany.
  • Steuernagel B; Institute for Plant Sciences, University of Cologne, Cologne, Germany.
  • Hayta S; Cluster of Excellence on Plant Sciences (CEPLAS), Cologne, Germany.
  • Smedley M; Plant Science Program, Biological and Environmental Science and Engineering Division (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia.
  • Harwood W; Center for Desert Agriculture, KAUST, Thuwal, Saudi Arabia.
  • Patpour M; John Innes Centre, Norwich Research Park, Norwich, UK.
  • Wu S; John Innes Centre, Norwich Research Park, Norwich, UK.
  • Poland J; John Innes Centre, Norwich Research Park, Norwich, UK.
  • Jones JDG; John Innes Centre, Norwich Research Park, Norwich, UK.
  • Reuber TL; John Innes Centre, Norwich Research Park, Norwich, UK.
  • Ronen M; John Innes Centre, Norwich Research Park, Norwich, UK.
  • Sharon A; John Innes Centre, Norwich Research Park, Norwich, UK.
  • Rouse MN; Department of Agroecology, Aarhus University, Slagelse, Denmark.
  • Xu S; Department of Plant Pathology, Kansas State University, Manhattan, KS, USA.
  • Holusová K; Plant Science Program, Biological and Environmental Science and Engineering Division (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia.
  • Bartos J; Center for Desert Agriculture, KAUST, Thuwal, Saudi Arabia.
  • Molnár I; Department of Plant Pathology, Kansas State University, Manhattan, KS, USA.
  • Karafiátová M; The Sainsbury Laboratory, University of East Anglia, Norwich, UK.
  • Hirt H; 2Blades Foundation, Evanston, IL, USA.
  • Blilou I; Enko Chem, Mystic, CT, USA.
  • Jaremko L; Institute for Cereal Crops Research, Tel Aviv University, Tel Aviv, Israel.
  • Dolezel J; Institute for Cereal Crops Research, and the School of Plant Sciences and Food Security, Tel Aviv University, Tel Aviv, Israel.
  • Steffenson BJ; Department of Plant Pathology, University of Minnesota, St. Paul, MN, USA.
  • Wulff BBH; USDA-ARS, Cereal Disease Laboratory, St. Paul, MN, USA.
Nat Genet ; 55(6): 921-926, 2023 06.
Article de En | MEDLINE | ID: mdl-37217714
ABSTRACT
To safeguard bread wheat against pests and diseases, breeders have introduced over 200 resistance genes into its genome, thus nearly doubling the number of designated resistance genes in the wheat gene pool1. Isolating these genes facilitates their fast-tracking in breeding programs and incorporation into polygene stacks for more durable resistance. We cloned the stem rust resistance gene Sr43, which was crossed into bread wheat from the wild grass Thinopyrum elongatum2,3. Sr43 encodes an active protein kinase fused to two domains of unknown function. The gene, which is unique to the Triticeae, appears to have arisen through a gene fusion event 6.7 to 11.6 million years ago. Transgenic expression of Sr43 in wheat conferred high levels of resistance to a wide range of isolates of the pathogen causing stem rust, highlighting the potential value of Sr43 in resistance breeding and engineering.
Sujet(s)
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Basidiomycota / Résistance à la maladie Langue: En Journal: Nat Genet Sujet du journal: GENETICA MEDICA Année: 2023 Type de document: Article Pays d'affiliation: Arabie saoudite
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Basidiomycota / Résistance à la maladie Langue: En Journal: Nat Genet Sujet du journal: GENETICA MEDICA Année: 2023 Type de document: Article Pays d'affiliation: Arabie saoudite