Assessment of sarcomere shortening and calcium transient in primary human and dog ventricular myocytes.

Gao, BaoXi; Abi-Gerges, Najah; Truong, Ky; Stafford, Alexa; Nguyen, William; Sutherland, Weston; Vargas, Hugo M; Qu, Yusheng

Gao, BaoXi; Abi-Gerges, Najah; Truong, Ky; Stafford, Alexa; Nguyen, William; Sutherland, Weston; Vargas, Hugo M; Qu, Yusheng.

Affiliation

Gao B; Amgen Research, Translational Safety & Bioanalytical Sciences, Amgen Inc, 1 Amgen Center Drive, Thousand Oaks, CA 91320, USA. Electronic address: Bgao@amgen.com.
Abi-Gerges N; AnaBios Corporation, 3030 Bunker Hill St, San Diego, CA 92109, USA.
Truong K; AnaBios Corporation, 3030 Bunker Hill St, San Diego, CA 92109, USA.
Stafford A; AnaBios Corporation, 3030 Bunker Hill St, San Diego, CA 92109, USA.
Nguyen W; AnaBios Corporation, 3030 Bunker Hill St, San Diego, CA 92109, USA.
Sutherland W; Amgen Research, Translational Safety & Bioanalytical Sciences, Amgen Inc, 1 Amgen Center Drive, Thousand Oaks, CA 91320, USA.
Vargas HM; Amgen Research, Translational Safety & Bioanalytical Sciences, Amgen Inc, 1 Amgen Center Drive, Thousand Oaks, CA 91320, USA.
Qu Y; Amgen Research, Translational Safety & Bioanalytical Sciences, Amgen Inc, 1 Amgen Center Drive, Thousand Oaks, CA 91320, USA.

J Pharmacol Toxicol Methods ; 123: 107278, 2023.

Article de En | MEDLINE | ID: mdl-37268094

Sujet(s)
Mots clés

Calcium transients; Dog myocytes; Human myocytes; Inotropes; Isolated myocytes; Sarcomere shortening

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Transplantation cardiaque / Myocytes cardiaques Limites: Animals / Humans Langue: En Journal: J Pharmacol Toxicol Methods Sujet du journal: FARMACOLOGIA / TOXICOLOGIA Année: 2023 Type de document: Article Pays de publication: États-Unis d'Amérique

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