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T-SPOT.TB Reactivity in Southern African Children With and Without in Utero Human Immunodeficiency Virus Exposure.
Iwase, Saori C; Edlefsen, Paul T; Bhebhe, Lynnette; Motsumi, Kesego; Moyo, Sikhulile; Happel, Anna-Ursula; Shao, Danica; Mmasa, Nicholas; Schenkel, Sara; Gasper, Melanie A; Dubois, Melanie; Files, Megan A; Seshadri, Chetan; Duffy, Fergal; Aitchison, John; Netea, Mihai G; Jao, Jennifer; Cameron, Donald W; Gray, Clive M; Jaspan, Heather B; Powis, Kathleen M.
Affiliation
  • Iwase SC; Division of Immunology, Department of Pathology, University of Cape Town, Cape Town, South Africa.
  • Edlefsen PT; Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.
  • Bhebhe L; Vaccine and Infectious Disease Division, Statistical Center for HIV/AIDS Research and Prevention, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
  • Motsumi K; Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana.
  • Moyo S; Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana.
  • Happel AU; Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana.
  • Shao D; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
  • Mmasa N; Division of Immunology, Department of Pathology, University of Cape Town, Cape Town, South Africa.
  • Schenkel S; Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.
  • Gasper MA; Vaccine and Infectious Disease Division, Statistical Center for HIV/AIDS Research and Prevention, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
  • Dubois M; Surgical Department, County Durham and Darlington NHS Trust, Darlington Memorial Hospital, Darlington, United Kingdom.
  • Files MA; Division of Pediatric Global Health, Massachusetts General Hospital, Boston, Massachusetts, USA.
  • Seshadri C; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.
  • Duffy F; Division of Pediatric Global Health, Massachusetts General Hospital, Boston, Massachusetts, USA.
  • Aitchison J; Division of Infectious Diseases, Department of Pediatrics, Boston Children's Hospital, Boston, Massachusetts, USA.
  • Netea MG; Department of Medicine, University of Washington School of Medicine, Seattle, Washington, USA.
  • Jao J; Department of Medicine, University of Washington School of Medicine, Seattle, Washington, USA.
  • Cameron DW; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.
  • Gray CM; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.
  • Jaspan HB; Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.
  • Powis KM; Department of Immunology and Metabolism, Life & Medical Sciences Institute, University of Bonn, Bonn, Germany.
Clin Infect Dis ; 77(8): 1133-1136, 2023 10 13.
Article de En | MEDLINE | ID: mdl-37293702
ABSTRACT
Infants who are human immunodeficiency virus (HIV)-exposed uninfected (iHEU) experience higher risk of infectious morbidity than infants HIV-unexposed uninfected (iHUU). We compared tuberculosis (TB) infection prevalence in 418 Bacillus Calmette-Guérin vaccinated sub-Saharan African iHEU and iHUU aged 9-18 months using T-SPOT.TB. Prevalence of TB infection was low and did not differ by HIV exposure status.
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Tuberculose / Infections à VIH / Tuberculose latente Type d'étude: Risk_factors_studies Limites: Child / Humans / Infant Langue: En Journal: Clin Infect Dis Sujet du journal: DOENCAS TRANSMISSIVEIS Année: 2023 Type de document: Article Pays d'affiliation: République d'Afrique du Sud
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Tuberculose / Infections à VIH / Tuberculose latente Type d'étude: Risk_factors_studies Limites: Child / Humans / Infant Langue: En Journal: Clin Infect Dis Sujet du journal: DOENCAS TRANSMISSIVEIS Année: 2023 Type de document: Article Pays d'affiliation: République d'Afrique du Sud