Structural and mechanistic basis of neutralization by a pan-hantavirus protective antibody.

Mittler, Eva; Serris, Alexandra; Esterman, Emma S; Florez, Catalina; Polanco, Laura C; O'Brien, Cecilia M; Slough, Megan M; Tynell, Janne; Gröning, Remigius; Sun, Yan; Abelson, Dafna M; Wec, Anna Z; Haslwanter, Denise; Keller, Markus; Ye, Chunyan; Bakken, Russel R; Jangra, Rohit K; Dye, John M; Ahlm, Clas; Rappazzo, C Garrett; Ulrich, Rainer G; Zeitlin, Larry; Geoghegan, James C; Bradfute, Steven B; Sidoli, Simone; Forsell, Mattias N E; Strandin, Tomas; Rey, Felix A; Herbert, Andrew S; Walker, Laura M; Chandran, Kartik; Guardado-Calvo, Pablo

Mittler, Eva; Serris, Alexandra; Esterman, Emma S; Florez, Catalina; Polanco, Laura C; O'Brien, Cecilia M; Slough, Megan M; Tynell, Janne; Gröning, Remigius; Sun, Yan; Abelson, Dafna M; Wec, Anna Z; Haslwanter, Denise; Keller, Markus; Ye, Chunyan; Bakken, Russel R; Jangra, Rohit K; Dye, John M; Ahlm, Clas; Rappazzo, C Garrett; Ulrich, Rainer G; Zeitlin, Larry; Geoghegan, James C; Bradfute, Steven B; Sidoli, Simone; Forsell, Mattias N E; Strandin, Tomas; Rey, Felix A; Herbert, Andrew S; Walker, Laura M; Chandran, Kartik; Guardado-Calvo, Pablo.

Affiliation

Mittler E; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Serris A; Institut Pasteur, Université Paris Cité, CNRS UMR3569, Structural Virology Unit, F-75015 Paris, France.
Esterman ES; Adimab LLC, Lebanon, NH 03766, USA.
Florez C; U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD 21702, USA.
Polanco LC; The Geneva Foundation, Tacoma, WA 98402, USA.
O'Brien CM; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Slough MM; U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD 21702, USA.
Tynell J; The Geneva Foundation, Tacoma, WA 98402, USA.
Gröning R; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Sun Y; Department of Clinical Microbiology, Umeå University, 90187 Umeå, Sweden.
Abelson DM; Zoonosis Unit, Department of Virology, Medical Faculty, University of Helsinki, 00290 Helsinki, Finland.
Wec AZ; Department of Clinical Microbiology, Umeå University, 90187 Umeå, Sweden.
Haslwanter D; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Keller M; Mapp Biopharmaceutical Inc., San Diego, CA 92121, USA.
Ye C; Adimab LLC, Lebanon, NH 03766, USA.
Bakken RR; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Jangra RK; Institute of Novel and Emerging Infectious Diseases, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, 17493 Greifswald-Insel Riems, Germany.
Dye JM; Center for Global Health, Department of Internal Medicine, University of New Mexico Health Science Center, Albuquerque, NM 87131, USA.
Ahlm C; U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD 21702, USA.
Rappazzo CG; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Ulrich RG; U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD 21702, USA.
Zeitlin L; Department of Clinical Microbiology, Umeå University, 90187 Umeå, Sweden.
Geoghegan JC; Adimab LLC, Lebanon, NH 03766, USA.
Bradfute SB; Institute of Novel and Emerging Infectious Diseases, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, 17493 Greifswald-Insel Riems, Germany.
Sidoli S; Partner site: Hamburg-Lübeck-Borstel-Riems, German Centre for Infection Research (DZIF), 17493 Greifswald-Insel Riems, Germany.
Forsell MNE; Mapp Biopharmaceutical Inc., San Diego, CA 92121, USA.
Strandin T; Adimab LLC, Lebanon, NH 03766, USA.
Rey FA; Center for Global Health, Department of Internal Medicine, University of New Mexico Health Science Center, Albuquerque, NM 87131, USA.
Herbert AS; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Walker LM; Department of Clinical Microbiology, Umeå University, 90187 Umeå, Sweden.
Chandran K; Zoonosis Unit, Department of Virology, Medical Faculty, University of Helsinki, 00290 Helsinki, Finland.
Guardado-Calvo P; Institut Pasteur, Université Paris Cité, CNRS UMR3569, Structural Virology Unit, F-75015 Paris, France.

Sci Transl Med ; 15(700): eadg1855, 2023 06 14.

Article de En | MEDLINE | ID: mdl-37315110

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Orthohantavirus / Anticorps antiviraux Limites: Humans Langue: En Journal: Sci Transl Med Sujet du journal: CIENCIA / MEDICINA Année: 2023 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: États-Unis d'Amérique

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