Minimum information and guidelines for reporting a Multiplexed Assay of Variant Effect.
ArXiv
; 2023 Jun 26.
Article
de En
| MEDLINE
| ID: mdl-37426450
ABSTRACT
Multiplexed Assays of Variant Effect (MAVEs) have emerged as a powerful approach for interrogating thousands of genetic variants in a single experiment. The flexibility and widespread adoption of these techniques across diverse disciplines has led to a heterogeneous mix of data formats and descriptions, which complicates the downstream use of the resulting datasets. To address these issues and promote reproducibility and reuse of MAVE data, we define a set of minimum information standards for MAVE data and metadata and outline a controlled vocabulary aligned with established biomedical ontologies for describing these experimental designs.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Type d'étude:
Guideline
Langue:
En
Journal:
ArXiv
Année:
2023
Type de document:
Article
Pays d'affiliation:
États-Unis d'Amérique