MYC overrides HIF-1&#945; to regulate proliferating primary cell metabolism in hypoxia.

Copeland, Courtney A; Olenchock, Benjamin A; Ziehr, David; McGarrity, Sarah; Leahy, Kevin; Young, Jamey D; Loscalzo, Joseph; Oldham, William M

MYC overrides HIF-1α to regulate proliferating primary cell metabolism in hypoxia.

Copeland, Courtney A; Olenchock, Benjamin A; Ziehr, David; McGarrity, Sarah; Leahy, Kevin; Young, Jamey D; Loscalzo, Joseph; Oldham, William M.

Affiliation

Copeland CA; Department of Medicine, Brigham and Women's Hospital, Boston, United States.
Olenchock BA; Department of Medicine, Harvard Medical School, Boston, United States.
Ziehr D; Department of Medicine, Brigham and Women's Hospital, Boston, United States.
McGarrity S; Department of Medicine, Harvard Medical School, Boston, United States.
Leahy K; Department of Medicine, Brigham and Women's Hospital, Boston, United States.
Young JD; Department of Medicine, Harvard Medical School, Boston, United States.
Loscalzo J; Department of Medicine, Massachusetts General Hospital, Boston, United States.
Oldham WM; Department of Medicine, Brigham and Women's Hospital, Boston, United States.

Elife ; 122023 07 10.

Article de En | MEDLINE | ID: mdl-37428010

Sujet(s)
Mots clés

MYC; biochemistry; cell biology; chemical biology; human; hypoxia; hypoxia-inducible factor; metabolic flux analysis; prolyl hydroxylase

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Transduction du signal / Protéines proto-oncogènes c-myc Type d'étude: Prognostic_studies Limites: Humans Langue: En Journal: Elife Année: 2023 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: Royaume-Uni

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