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NOS inhibition reverses TLR2-induced chondrocyte dysfunction and attenuates age-related osteoarthritis.
Shen, Ping; Serve, Sebastian; Wu, Peihua; Liu, Xiaohui; Dai, Yujie; Durán-Hernández, Nayar; Nguyen, Dan Thi Mai; Fuchs, Michael; Maleitzke, Tazio; Reisener, Marie-Jacqueline; Dzamukova, Maria; Nussbaumer, Katrin; Brunner, Tobias M; Li, Yonghai; Holecska, Vivien; Heinz, Gitta A; Heinrich, Frederik; Durek, Pawel; Katsoula, Georgia; Gwinner, Clemens; Jung, Tobias; Zeggini, Eleftheria; Winkler, Tobias; Mashreghi, Mir-Farzin; Pumberger, Matthias; Perka, Carsten; Löhning, Max.
Affiliation
  • Shen P; Pitzer Laboratory of Osteoarthritis Research, German Rheumatism Research Center, a Leibniz Institute, 10117 Berlin, Germany.
  • Serve S; Experimental Immunology and Osteoarthritis Research, Department of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117 Berlin, Germany.
  • Wu P; Stem Cell and Biotherapy Engineering Research Center of Henan Province, College of Life Sciences and Technology, Xinxiang Medical University, 453003 Xinxiang, China.
  • Liu X; Pitzer Laboratory of Osteoarthritis Research, German Rheumatism Research Center, a Leibniz Institute, 10117 Berlin, Germany.
  • Dai Y; Experimental Immunology and Osteoarthritis Research, Department of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117 Berlin, Germany.
  • Durán-Hernández N; Pitzer Laboratory of Osteoarthritis Research, German Rheumatism Research Center, a Leibniz Institute, 10117 Berlin, Germany.
  • Nguyen DTM; Experimental Immunology and Osteoarthritis Research, Department of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117 Berlin, Germany.
  • Fuchs M; Pitzer Laboratory of Osteoarthritis Research, German Rheumatism Research Center, a Leibniz Institute, 10117 Berlin, Germany.
  • Maleitzke T; Experimental Immunology and Osteoarthritis Research, Department of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117 Berlin, Germany.
  • Reisener MJ; Pitzer Laboratory of Osteoarthritis Research, German Rheumatism Research Center, a Leibniz Institute, 10117 Berlin, Germany.
  • Dzamukova M; Experimental Immunology and Osteoarthritis Research, Department of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117 Berlin, Germany.
  • Nussbaumer K; Pitzer Laboratory of Osteoarthritis Research, German Rheumatism Research Center, a Leibniz Institute, 10117 Berlin, Germany.
  • Brunner TM; Experimental Immunology and Osteoarthritis Research, Department of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117 Berlin, Germany.
  • Li Y; Pitzer Laboratory of Osteoarthritis Research, German Rheumatism Research Center, a Leibniz Institute, 10117 Berlin, Germany.
  • Holecska V; Experimental Immunology and Osteoarthritis Research, Department of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117 Berlin, Germany.
  • Heinz GA; Department of Orthopaedic Surgery, University of Ulm, 89081 Ulm, Germany.
  • Heinrich F; Center for Musculoskeletal Surgery, Charité-Universitätsmedizin Berlin, Corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117 Berlin, Germany.
  • Durek P; Julius Wolff Institute, Berlin Institute of Health at Charité-Universitätsmedizin Berlin, 13353 Berlin, Germany.
  • Katsoula G; Berlin Institute of Health Charité Clinician Scientist Program, BIH Biomedical Innovation Academy, Berlin Institute of Health at Charité-Universitätsmedizin, 10178 Berlin, Germany.
  • Gwinner C; Center for Musculoskeletal Surgery, Charité-Universitätsmedizin Berlin, Corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117 Berlin, Germany.
  • Jung T; Pitzer Laboratory of Osteoarthritis Research, German Rheumatism Research Center, a Leibniz Institute, 10117 Berlin, Germany.
  • Zeggini E; Experimental Immunology and Osteoarthritis Research, Department of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117 Berlin, Germany.
  • Winkler T; Pitzer Laboratory of Osteoarthritis Research, German Rheumatism Research Center, a Leibniz Institute, 10117 Berlin, Germany.
  • Mashreghi MF; Pitzer Laboratory of Osteoarthritis Research, German Rheumatism Research Center, a Leibniz Institute, 10117 Berlin, Germany.
  • Pumberger M; Experimental Immunology and Osteoarthritis Research, Department of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117 Berlin, Germany.
  • Perka C; Stem Cell and Biotherapy Engineering Research Center of Henan Province, College of Life Sciences and Technology, Xinxiang Medical University, 453003 Xinxiang, China.
  • Löhning M; Pitzer Laboratory of Osteoarthritis Research, German Rheumatism Research Center, a Leibniz Institute, 10117 Berlin, Germany.
Proc Natl Acad Sci U S A ; 120(29): e2207993120, 2023 07 18.
Article de En | MEDLINE | ID: mdl-37428931
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Arthrose / Cartilage articulaire Limites: Animals / Humans Langue: En Journal: Proc Natl Acad Sci U S A Année: 2023 Type de document: Article Pays d'affiliation: Allemagne Pays de publication: États-Unis d'Amérique
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Arthrose / Cartilage articulaire Limites: Animals / Humans Langue: En Journal: Proc Natl Acad Sci U S A Année: 2023 Type de document: Article Pays d'affiliation: Allemagne Pays de publication: États-Unis d'Amérique