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LRP8-mediated selenocysteine uptake is a targetable vulnerability in MYCN-amplified neuroblastoma.
Alborzinia, Hamed; Chen, Zhiyi; Yildiz, Umut; Freitas, Florencio Porto; Vogel, Felix C E; Varga, Julianna Patricia; Batani, Jasmin; Bartenhagen, Christoph; Schmitz, Werner; Büchel, Gabriele; Michalke, Bernhard; Zheng, Jashuo; Meierjohann, Svenja; Girardi, Enrico; Espinet, Elisa; Flórez, Andrés F; Dos Santos, Ancely Ferreira; Aroua, Nesrine; Cheytan, Tasneem; Haenlin, Julie; Schlicker, Lisa; Xavier da Silva, Thamara N; Przybylla, Adriana; Zeisberger, Petra; Superti-Furga, Giulio; Eilers, Martin; Conrad, Marcus; Fabiano, Marietta; Schweizer, Ulrich; Fischer, Matthias; Schulze, Almut; Trumpp, Andreas; Friedmann Angeli, José Pedro.
Affiliation
  • Alborzinia H; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM GmbH), Heidelberg, Germany.
  • Chen Z; Division of Stem Cells and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Yildiz U; Rudolf Virchow Zentrum (RVZ), Center for Integrative and Translational Bioimaging, University of Würzburg, Würzburg, Germany.
  • Freitas FP; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM GmbH), Heidelberg, Germany.
  • Vogel FCE; Division of Stem Cells and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Varga JP; European Molecular Biology Laboratory, Genome Biology Unit, Heidelberg, Germany.
  • Batani J; Rudolf Virchow Zentrum (RVZ), Center for Integrative and Translational Bioimaging, University of Würzburg, Würzburg, Germany.
  • Bartenhagen C; Division of Tumor Metabolism and Microenvironment, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Schmitz W; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM GmbH), Heidelberg, Germany.
  • Büchel G; Division of Stem Cells and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Michalke B; European Molecular Biology Organization, Heidelberg, Germany.
  • Zheng J; Rudolf Virchow Zentrum (RVZ), Center for Integrative and Translational Bioimaging, University of Würzburg, Würzburg, Germany.
  • Meierjohann S; Center for Molecular Medicine Cologne (CMMC) and Department of Experimental Pediatric Oncology, University Children's Hospital, Medical Faculty, University of Cologne, Cologne, Germany.
  • Girardi E; Department of Biochemistry and Molecular Biology, Theodor Boveri Institute, Biocenter, University of Würzburg, Würzburg, Germany.
  • Espinet E; Mildred Scheel Early Career Center, University Hospital Würzburg, Würzburg, Germany.
  • Flórez AF; Research Unit Analytical BioGeoChemistry, Helmholtz Center München (HMGU), Neuherberg, Germany.
  • Dos Santos AF; Institute of Metabolism and Cell Death, Helmholtz Zentrum München (HMGU), Neuherberg, Germany.
  • Aroua N; Department of Pathology, University of Würzburg, Würzburg, Germany.
  • Cheytan T; CeMM-Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
  • Haenlin J; Solgate GmbH, Klosterneuburg, Austria.
  • Schlicker L; Anatomy Unit, Department of Pathology and Experimental Therapy, School of Medicine, University of Barcelona (UB), L'Hospitalet de Llobregat, Barcelona, Spain.
  • Xavier da Silva TN; Molecular Mechanisms and Experimental Therapy in Oncology Program (Oncobell), Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain.
  • Przybylla A; Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA, USA.
  • Zeisberger P; Rudolf Virchow Zentrum (RVZ), Center for Integrative and Translational Bioimaging, University of Würzburg, Würzburg, Germany.
  • Superti-Furga G; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM GmbH), Heidelberg, Germany.
  • Eilers M; Division of Stem Cells and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Conrad M; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM GmbH), Heidelberg, Germany.
  • Fabiano M; Division of Stem Cells and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Schweizer U; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM GmbH), Heidelberg, Germany.
  • Fischer M; Division of Stem Cells and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Schulze A; Division of Tumor Metabolism and Microenvironment, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Trumpp A; Division of Tumor Metabolism and Microenvironment, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Friedmann Angeli JP; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM GmbH), Heidelberg, Germany.
EMBO Mol Med ; 15(8): e18014, 2023 08 07.
Article de En | MEDLINE | ID: mdl-37435859
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Ferroptose / Neuroblastome Type d'étude: Prognostic_studies Limites: Animals / Humans Langue: En Journal: EMBO Mol Med Sujet du journal: BIOLOGIA MOLECULAR Année: 2023 Type de document: Article Pays d'affiliation: Allemagne
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Ferroptose / Neuroblastome Type d'étude: Prognostic_studies Limites: Animals / Humans Langue: En Journal: EMBO Mol Med Sujet du journal: BIOLOGIA MOLECULAR Année: 2023 Type de document: Article Pays d'affiliation: Allemagne