Chondroitin Polymerizing Factor (CHPF) promotes cell proliferation and tumor growth in human osteosarcoma by inhibiting SKP2's ubiquitination while activating the AKT pathway.

Shen, Yi; Li, Jun; Peng, Dan; Liao, Lele; Chen, Xia; Zhong, Weiye; Liu, Zicheng; Yu, Chao; Sun, Yuanliang

Shen, Yi; Li, Jun; Peng, Dan; Liao, Lele; Chen, Xia; Zhong, Weiye; Liu, Zicheng; Yu, Chao; Sun, Yuanliang.

Affiliation

Shen Y; Department of Orthopaedics, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410000, China.
Li J; Department of Orthopaedics, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410000, China.
Peng D; Department of Orthopaedics, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410000, China.
Liao L; Department of Orthopaedics, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410000, China.
Chen X; Department of Orthopaedics, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410000, China.
Zhong W; Department of Orthopaedics, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410000, China.
Liu Z; Department of Orthopaedics, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410000, China.
Yu C; Department of Orthopaedics, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410000, China.
Sun Y; Department of Spine Surgery, Affiliated Hospital of Qingdao University, Qingdao, Shandong 266000, China.

Genes Dis ; 10(5): 2125-2136, 2023 Sep.

Article de En | MEDLINE | ID: mdl-37492722

Mots clés

Akt signaling pathway; CHPF; Osteosarcoma; SKP2; Ubiquitination

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Langue: En Journal: Genes Dis Année: 2023 Type de document: Article Pays d'affiliation: Chine Pays de publication: Pays-Bas

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