Nasal polyposis from cystic fibrosis in children - the experience of a single center.
Rom J Morphol Embryol
; 64(2): 235-240, 2023.
Article
de En
| MEDLINE
| ID: mdl-37518881
ABSTRACT
BACKGROUND:
Cystic fibrosis (CF) is the most common monogenic disease, characterized by clinically notable polymorphism. Respiratory disease is the main factor that influences the disease outcome and prognosis of the patient with CF, bacterial infections being responsible for severe exacerbations and rhinosinusitis a difficult complication, besides lung disease.AIM:
The aim of the paper was to present a case series of CF-associated nasal polyposis and our management experience, providing new data for nasal and sinus complications. PATIENTS, MATERIALS ANDMETHODS:
Patients attending the National Cystic Fibrosis Center, Timisoara, Romania, were evaluated for nasal polyposis. Besides clinical examination, endoscopy, and computed tomography (CT) was performed for comprehensive evaluation. Patients with persistent symptoms or with complicated sinusitis underwent surgical approach.RESULTS:
Fourteen (18.18%) children were diagnosed with nasal polyposis and had surgery, with positive outcomes. One patient received Omalizumab for an associated, uncontrolled asthma with a subsequent substantial effect with the significant polyp reduction and lack of recurrence.CONCLUSIONS:
Even if extremely difficult to manage, complicated nasal polyposis CF related might have an improved outcome and better life quality.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Type d'étude:
Prognostic_studies
Langue:
En
Journal:
Rom J Morphol Embryol
Sujet du journal:
ANATOMIA
/
EMBRIOLOGIA
Année:
2023
Type de document:
Article