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Dramatic efficacy of cannabidiol on refractory chronic pain in an adolescent with sickle cell disease.
Mayrand, Lara; Tarbé de Saint Hardouin, Anne-Laure; Maciel, Thiago Trovati; Rignault-Bricard, Rachel; Taylor, Melissa; Brice, Joséphine; de Montalembert, Mariane; Hermine, Olivier; Greco, Céline; Allali, Slimane.
Affiliation
  • Mayrand L; Laboratory of Cellular and Molecular Mechanisms of Hematological Disorders and Therapeutical Implications, Imagine Institute, Inserm U1163, Université Paris Cité, Paris, France.
  • Tarbé de Saint Hardouin AL; Department of General Pediatrics and Pediatric Infectious Diseases, Sickle Cell Center, Necker-Enfants Malades Hospital, Assistance Publique - Hôpitaux de Paris (AP-HP), Université Paris Cité, Paris, France.
  • Maciel TT; Department of Pain and Palliative Care Unit, Necker-Enfants Malades Hospital, AP-HP, Université Paris Cité, Paris, France.
  • Rignault-Bricard R; Department of Pain and Palliative Care Unit, Necker-Enfants Malades Hospital, AP-HP, Université Paris Cité, Paris, France.
  • Taylor M; Laboratory of Cellular and Molecular Mechanisms of Hematological Disorders and Therapeutical Implications, Imagine Institute, Inserm U1163, Université Paris Cité, Paris, France.
  • Brice J; Laboratory of Excellence GR-Ex, Paris, France.
  • de Montalembert M; Laboratory of Cellular and Molecular Mechanisms of Hematological Disorders and Therapeutical Implications, Imagine Institute, Inserm U1163, Université Paris Cité, Paris, France.
  • Hermine O; Laboratory of Excellence GR-Ex, Paris, France.
  • Greco C; Department of General Pediatrics and Pediatric Infectious Diseases, Sickle Cell Center, Necker-Enfants Malades Hospital, Assistance Publique - Hôpitaux de Paris (AP-HP), Université Paris Cité, Paris, France.
  • Allali S; Laboratory of Excellence GR-Ex, Paris, France.
Am J Hematol ; 98(11): E295-E297, 2023 Nov.
Article de En | MEDLINE | ID: mdl-37540761
ABSTRACT
Here, we report a dramatic efficacy of cannabidiol in an adolescent with SCD suffering from chronic pain refractory to other analgesics, with complete regression of chronic pain and rapid plasma histamine level normalization after treatment.

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Langue: En Journal: Am J Hematol Année: 2023 Type de document: Article Pays d'affiliation: France

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Langue: En Journal: Am J Hematol Année: 2023 Type de document: Article Pays d'affiliation: France