Reversing the Inflammatory Process-25 Years of Tumor Necrosis Factor-α Inhibitors.
J Clin Med
; 12(15)2023 Jul 31.
Article
de En
| MEDLINE
| ID: mdl-37568441
ABSTRACT
Immune-mediated inflammatory diseases, such as rheumatoid arthritis, psoriatic arthritis, peripheral and/or axial spondyloarthritis, Crohn's disease, and ulcerative colitis, are characterized by molecular and cellular changes in the immune system. Due to the systemic nature of these diseases, organs such as the liver or cardiovascular system are often affected by the inflammatory process. Tumor necrosis factor-α inhibitor therapy reduces the activation of pro-inflammatory signaling cascades, mitigates the chronic inflammatory process by restoring cellular balance, and alleviates clinical consequences, such as pain and tissue damage.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Langue:
En
Journal:
J Clin Med
Année:
2023
Type de document:
Article
Pays d'affiliation:
Allemagne