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Alzheimer's disease linked Aß42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling.
Zoltowska, Katarzyna Marta; Das, Utpal; Lismont, Sam; Enzlein, Thomas; Maesako, Masato; Houser, Mei Cq; Franco, María Luisa; Moreira, Diana Gomes; Karachentsev, Dmitry; Becker, Ann; Hopf, Carsten; Vilar, Marçal; Berezovska, Oksana; Mobley, William; Chávez-Gutiérrez, Lucía.
Affiliation
  • Zoltowska KM; VIB-KU Leuven Center for Brain & Disease Research, VIB, Leuven, Belgium.
  • Das U; Department of Neurosciences, University of California San Diego, La Jolla, CA, United States of America.
  • Lismont S; VIB-KU Leuven Center for Brain & Disease Research, VIB, Leuven, Belgium.
  • Enzlein T; VIB-KU Leuven Center for Brain & Disease Research, VIB, Leuven, Belgium.
  • Maesako M; Center for Mass Spectrometry and Optical Spectroscopy (CeMOS), Mannheim University of Applied Sciences, Mannheim, Germany.
  • Houser MC; Department of Neurology, Massachusetts General Hospital/Harvard Medical School, Charlestown, MA, United States of America.
  • Franco ML; Department of Neurology, Massachusetts General Hospital/Harvard Medical School, Charlestown, MA, United States of America.
  • Moreira DG; Molecular Basis of Neurodegeneration Unit, Institute of Biomedicine of València (IBV-CSIC), València, Spain.
  • Karachentsev D; VIB-KU Leuven Center for Brain & Disease Research, VIB, Leuven, Belgium.
  • Becker A; Department of Neurosciences, University of California San Diego, La Jolla, CA, United States of America.
  • Hopf C; Department of Neurosciences, University of California San Diego, La Jolla, CA, United States of America.
  • Vilar M; Center for Mass Spectrometry and Optical Spectroscopy (CeMOS), Mannheim University of Applied Sciences, Mannheim, Germany.
  • Berezovska O; Medical Faculty, Heidelberg University, Heidelberg, Germany.
  • Mobley W; Mannheim Center for Translational Neuroscience (MCTN), Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany.
  • Chávez-Gutiérrez L; Molecular Basis of Neurodegeneration Unit, Institute of Biomedicine of València (IBV-CSIC), València, Spain.
bioRxiv ; 2023 Oct 28.
Article de En | MEDLINE | ID: mdl-37577527
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Langue: En Journal: BioRxiv Année: 2023 Type de document: Article Pays d'affiliation: Belgique
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Langue: En Journal: BioRxiv Année: 2023 Type de document: Article Pays d'affiliation: Belgique