Prognostic impact of early aortic volume changes at hospital discharge in patients with acute type B aortic dissection.
J Cardiol
; 83(1): 49-56, 2024 01.
Article
de En
| MEDLINE
| ID: mdl-37591338
ABSTRACT
BACKGROUND:
Early prediction of aorta-related events is important for determining subsequent treatment strategies in patients with acute aortic dissection. However, most studies evaluated long-term aortic growth rates by annual assessment. The purpose of our study was to determine whether the in-hospital growth rate of aortic volume was associated with aorta-related events.METHODS:
We studied 116 patients with uncomplicated type B acute aortic dissection. We analyzed whether changes in aortic volume were associated with aorta-related events during a 5-year follow-up. According to the growth rate from admission to discharge, patients were divided into two groups Increase >0 (aortic volume nâ¯=â¯59, aortic diameter nâ¯=â¯43) and Reduction ≤0 (aortic volume nâ¯=â¯57, aortic diameter nâ¯=â¯73) in maximum aortic diameter or aortic volume. The primary endpoint was the discriminative ability of the growth rate of aortic volume for aorta-related events.RESULTS:
According to the evaluation of aortic volume changes, the Increase group had significantly higher aorta-related event rates than those in the Reduction group (49.2â¯% vs. 3.5â¯%, respectively; pâ¯<â¯0.001). Receiver operating characteristics analysis showed that the growth rate of aortic volume had a clearly useful discrimination, with an area under the curve of 0.84, whereas the discriminative ability of the growth rate of maximum aortic diameter was poor (area under the curve 0.53). Multivariate analysis showed that the growth rate of aortic volume from admission to discharge was an independent predictor of aorta-related events (hazard ratio, 26.3; 95â¯% confidence interval, 2.04-286.49; pâ¯=â¯0.001).CONCLUSIONS:
In-hospital evaluation of aortic volume was helpful to predict long-term aorta-related events in patients with uncomplicated type B acute aortic dissection.Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Anévrysme de l'aorte thoracique
/
795
Type d'étude:
Prognostic_studies
Limites:
Humans
Langue:
En
Journal:
J Cardiol
Sujet du journal:
CARDIOLOGIA
Année:
2024
Type de document:
Article
Pays d'affiliation:
Japon
Pays de publication:
Pays-Bas