The mTOR pathway genes <i>mTOR, Rheb, Depdc5, Pten</i>, and <i>Tsc1</i> have convergent and divergent impacts on cortical neuron development and function.

Nguyen, Lena H; Xu, Youfen; Nair, Maanasi; Bordey, Angelique

The mTOR pathway genes mTOR, Rheb, Depdc5, Pten, and Tsc1 have convergent and divergent impacts on cortical neuron development and function.

Nguyen, Lena H; Xu, Youfen; Nair, Maanasi; Bordey, Angelique.

Affiliation

Nguyen LH; Department Neuroscience, School of Behavioral and Brain Sciences, University of Texas at Dallas, Richardson, TX 75080, USA.
Xu Y; Departments of Neurosurgery and Cellular & Molecular Physiology, Wu Tsai Institute, Yale University School of Medicine, New Haven, CT 06510, USA.
Nair M; Departments of Neurosurgery and Cellular & Molecular Physiology, Wu Tsai Institute, Yale University School of Medicine, New Haven, CT 06510, USA.
Bordey A; Departments of Neurosurgery and Cellular & Molecular Physiology, Wu Tsai Institute, Yale University School of Medicine, New Haven, CT 06510, USA.

bioRxiv ; 2024 Jan 06.

Article de En | MEDLINE | ID: mdl-37609221

Mots clés

HCN4; action potential; epilepsy; malformation of cortical development; resting membrane potential; seizures; synaptic activity

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Langue: En Journal: BioRxiv Année: 2024 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: États-Unis d'Amérique

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