Ginsenosides in endometrium-related diseases: Emerging roles and mechanisms.
Biomed Pharmacother
; 166: 115340, 2023 Oct.
Article
de En
| MEDLINE
| ID: mdl-37625321
ABSTRACT
Ginsenosides, agents extracted from an important herb (ginseng), are expected to provide new therapies for endometrium-related diseases. Based on the molecular types of ginsenosides, we reviewed the main pharmacological effects of ginsenosides against endometrium-related diseases (e.g., endometrial cancers, endometriosis, and endometritis). The mechanism of action of ginsenosides involves inducing apoptosis of endometrium-related cells, promoting autophagy of endometrium-related cells, regulating epithelial-mesenchymal transition (EMT) in endometrium-related cells, and activating the immune system to kill cells associated with endometrial diseases. We hope to provide a theoretical foundation for the treatment of endometrium-related diseases by ginsenosides.
Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Maladies de l'utérus
/
Tumeurs de l'endomètre
/
Ginsénosides
/
Endométriose
Limites:
Female
/
Humans
Langue:
En
Journal:
Biomed Pharmacother
Année:
2023
Type de document:
Article