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Transformer-based biomarker prediction from colorectal cancer histology: A large-scale multicentric study.
Wagner, Sophia J; Reisenbüchler, Daniel; West, Nicholas P; Niehues, Jan Moritz; Zhu, Jiefu; Foersch, Sebastian; Veldhuizen, Gregory Patrick; Quirke, Philip; Grabsch, Heike I; van den Brandt, Piet A; Hutchins, Gordon G A; Richman, Susan D; Yuan, Tanwei; Langer, Rupert; Jenniskens, Josien C A; Offermans, Kelly; Mueller, Wolfram; Gray, Richard; Gruber, Stephen B; Greenson, Joel K; Rennert, Gad; Bonner, Joseph D; Schmolze, Daniel; Jonnagaddala, Jitendra; Hawkins, Nicholas J; Ward, Robyn L; Morton, Dion; Seymour, Matthew; Magill, Laura; Nowak, Marta; Hay, Jennifer; Koelzer, Viktor H; Church, David N; Matek, Christian; Geppert, Carol; Peng, Chaolong; Zhi, Cheng; Ouyang, Xiaoming; James, Jacqueline A; Loughrey, Maurice B; Salto-Tellez, Manuel; Brenner, Hermann; Hoffmeister, Michael; Truhn, Daniel; Schnabel, Julia A; Boxberg, Melanie; Peng, Tingying; Kather, Jakob Nikolas.
Affiliation
  • Wagner SJ; Helmholtz Munich - German Research Center for Environment and Health, Munich, Germany; School of Computation, Information and Technology, Technical University of Munich, Munich, Germany; Else Kroener Fresenius Center for Digital Health (EFFZ), Technical University Dresden, Dresden, Germany.
  • Reisenbüchler D; Helmholtz Munich - German Research Center for Environment and Health, Munich, Germany.
  • West NP; Institute of Pathology, University Medical Center Mainz, Mainz, Germany.
  • Niehues JM; Else Kroener Fresenius Center for Digital Health (EFFZ), Technical University Dresden, Dresden, Germany.
  • Zhu J; Else Kroener Fresenius Center for Digital Health (EFFZ), Technical University Dresden, Dresden, Germany.
  • Foersch S; Institute of Pathology, University Medical Center Mainz, Mainz, Germany.
  • Veldhuizen GP; Else Kroener Fresenius Center for Digital Health (EFFZ), Technical University Dresden, Dresden, Germany.
  • Quirke P; Division of Pathology and Data Analytics, Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK.
  • Grabsch HI; Division of Pathology and Data Analytics, Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK; Department of Pathology, GROW School for Oncology and Developmental Biology, Maastricht University Medical Center+, Maastricht, the Netherlands.
  • van den Brandt PA; Department of Epidemiology, Maastricht University Medical Center+, Maastricht, the Netherlands.
  • Hutchins GGA; Division of Pathology and Data Analytics, Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK.
  • Richman SD; Division of Pathology and Data Analytics, Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK.
  • Yuan T; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Langer R; Institute of Pathology und Molecular Pathology, Johannes Kepler University Hospital Linz, Linz, Österreich.
  • Jenniskens JCA; Department of Epidemiology, Maastricht University Medical Center+, Maastricht, the Netherlands.
  • Offermans K; Department of Epidemiology, Maastricht University Medical Center+, Maastricht, the Netherlands.
  • Mueller W; Gemeinschaftspraxis Pathologie, Starnberg, Germany.
  • Gray R; Nuffield Department of Population Health, University of Oxford, Oxford, UK.
  • Gruber SB; Center for Precision Medicine and Department of Medical Oncology, City of Hope National Medical Center, Duarte, CA, USA.
  • Greenson JK; Department of Pathology, City of Hope Comprehensive Cancer Center, Duarte, CA, USA.
  • Rennert G; Department of Community Medicine & Epidemiology, Lady Davis Carmel Medical Center, Ruth & Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel; Steve and Cindy Rasmussen Institute for Genomic Medicine, Lady Davis Carmel Medical Center and Technion Facul
  • Bonner JD; Department of Community Medicine & Epidemiology, Lady Davis Carmel Medical Center, Ruth & Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
  • Schmolze D; Center for Precision Medicine and Department of Medical Oncology, City of Hope National Medical Center, Duarte, CA, USA.
  • Jonnagaddala J; School of Population Health, Faculty of Medicine and Health, UNSW Sydney, Sydney, NSW, Australia.
  • Hawkins NJ; School of Medical Sciences, Faculty of Medicine and Health, UNSW Sydney, Sydney, NSW, Australia.
  • Ward RL; School of Medical Sciences, Faculty of Medicine and Health, UNSW Sydney, Sydney, NSW, Australia; Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.
  • Morton D; University Hospital Birmingham, Birmingham, UK.
  • Seymour M; St James's University Hospital, Leeds, UK.
  • Magill L; University of Birmingham Clinical Trials Unit, Birmingham, UK.
  • Nowak M; Department of Pathology and Molecular Pathology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
  • Hay J; Glasgow Tissue Research Facility, University of Glasgow, Queen Elizabeth University Hospital, Glasgow, UK.
  • Koelzer VH; Department of Pathology and Molecular Pathology, University Hospital Zurich, University of Zurich, Zurich, Switzerland; Department of Oncology, University of Oxford, Oxford, UK; Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford, UK.
  • Church DN; Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford, UK; Oxford NIHR Comprehensive Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
  • Matek C; Helmholtz Munich - German Research Center for Environment and Health, Munich, Germany; Institute of Pathology, University Hospital Erlangen, FAU Erlangen-Nuremberg, Erlangen, Germany; Comprehensive Cancer Center Erlangen-EMN (CCC), University Hospital Erlangen, FAU Erlangen-Nuremberg, Erlangen, Germ
  • Geppert C; Institute of Pathology, University Hospital Erlangen, FAU Erlangen-Nuremberg, Erlangen, Germany; Comprehensive Cancer Center Erlangen-EMN (CCC), University Hospital Erlangen, FAU Erlangen-Nuremberg, Erlangen, Germany.
  • Peng C; Medical School, Jianggang Shan University, Jiangxi, China.
  • Zhi C; Department of Pathology, the Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
  • Ouyang X; Department of Pathology, the Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
  • James JA; Precision Medicine Centre of Excellence, Health Sciences Building, The Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK; Regional Molecular Diagnostic Service, Belfast Health and Social Care Trust, Belfast, UK; The Patrick G Johnston Centre for Cancer Research,
  • Loughrey MB; The Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK; Department of Cellular Pathology, Belfast Health and Social Care Trust, Belfast, UK; Centre for Public Health, Queen's University Belfast, Belfast, UK.
  • Salto-Tellez M; Precision Medicine Centre of Excellence, Health Sciences Building, The Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK; Regional Molecular Diagnostic Service, Belfast Health and Social Care Trust, Belfast, UK; Integrated Pathology Unit, Institute for Cancer Res
  • Brenner H; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany; Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany; German Cancer Consortium (DKTK), German Cancer Res
  • Hoffmeister M; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Truhn D; Department of Diagnostic and Interventional Radiology, University Hospital RWTH Aachen, Aachen, Germany.
  • Schnabel JA; Helmholtz Munich - German Research Center for Environment and Health, Munich, Germany; School of Computation, Information and Technology, Technical University of Munich, Munich, Germany; School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
  • Boxberg M; Institute of Pathology, Technical University Munich, Munich, Germany; Institute of Pathology Munich-North, Munich, Germany.
  • Peng T; Helmholtz Munich - German Research Center for Environment and Health, Munich, Germany. Electronic address: tingying.peng@helmholtz-munich.de.
  • Kather JN; Else Kroener Fresenius Center for Digital Health (EFFZ), Technical University Dresden, Dresden, Germany; Division of Pathology and Data Analytics, Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK; Medical Oncology, National Center for Tumor Diseases (NCT), University
Cancer Cell ; 41(9): 1650-1661.e4, 2023 09 11.
Article de En | MEDLINE | ID: mdl-37652006

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Algorithmes / Tumeurs colorectales Type d'étude: Clinical_trials / Prognostic_studies / Risk_factors_studies Limites: Humans Langue: En Journal: Cancer Cell Sujet du journal: NEOPLASIAS Année: 2023 Type de document: Article Pays d'affiliation: Allemagne

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Algorithmes / Tumeurs colorectales Type d'étude: Clinical_trials / Prognostic_studies / Risk_factors_studies Limites: Humans Langue: En Journal: Cancer Cell Sujet du journal: NEOPLASIAS Année: 2023 Type de document: Article Pays d'affiliation: Allemagne