[Solid Tumors With Cold Agglutinins:Report of Two Cases and Literature Review].
Zhongguo Yi Xue Ke Xue Yuan Xue Bao
; 45(4): 689-694, 2023 Aug.
Article
de Zh
| MEDLINE
| ID: mdl-37654151
ABSTRACT
Cold agglutinins(CA),autoantibodies against the antigen I or i on the surface of red blood cells,are mainly of IgM class,and the majority have κ light chains.They can lead to red blood cell agglutination at decreased body temperature and are usually associated with infections,drug reactions,autoimmune diseases,and hematological malignancies.However,solid tumors with CA are rare.We reported two cases of CA in the peripheral blood of patients with solid tumors.Peripheral complete blood cell count of the patients at admission showed reduced erythrocyte count and hematocrit,mismatching between erythrocyte count and hemoglobin,abnormally elevated levels of mean corpuscular hemoglobin and mean cell hemoglobin concentration.Peripheral blood smear showed erythrocyte aggregation.After the sample was preheated at 37 â for 30 min,the reversibility of red blood cell aggregation was observed,and the erythrocyte parameters were corrected.
Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Tumeurs de l'ovaire
/
Autoanticorps
/
Tumeurs du sein
Limites:
Female
/
Humans
Langue:
Zh
Journal:
Zhongguo Yi Xue Ke Xue Yuan Xue Bao
Année:
2023
Type de document:
Article
Pays d'affiliation:
Chine