Hospitalization risk among patients with Mpox infection-a propensity score matched analysis.
Ther Adv Infect Dis
; 10: 20499361231196683, 2023.
Article
de En
| MEDLINE
| ID: mdl-37663111
ABSTRACT
Background:
Monkeypox (Mpox) is a reemerging, neglected viral disease. By May 2023, worldwide Mpox cases surpassed 87,000. Predictive factors for hospitalization with Mpox are lacking.Objective:
We aim to compare clinical characteristics and outcomes in hospitalized and nonhospitalized patients with Mpox infection.Design:
A multicenter retrospective case-control cohort of patients with Mpox infection.Methods:
We performed a propensity score match analysis from a global health network (TrinetX). We compare clinical characteristics and outcomes between hospitalized and nonhospitalized patients with Mpox.Results:
Of 1477 patients, 6% were hospitalized, 52% required an ED visit, and 29% received treatment at urgent care. After propensity score matching, 80 patients remained in each group. Hospitalizations were more common among Black persons (51% versus 33%, p = 0.01), people with HIV (50% versus 20%, p < 0.0001), and those with proctitis (44% versus 12.5%, p < 0.001).Conclusion:
Independent predictive factors of hospitalization in our cohort for Mpox included people who are Black with a diagnosis of HIV, severe proctitis, pain requiring opioids, and elevated lactate dehydrogenase. Greater recognition of factors associated with increased risk of Mpox severity and hospitalization is paramount.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Type d'étude:
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Langue:
En
Journal:
Ther Adv Infect Dis
Année:
2023
Type de document:
Article
Pays d'affiliation:
États-Unis d'Amérique