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Intratumoral drug-releasing microdevices allow in situ high-throughput pharmaco phenotyping in patients with gliomas.
Peruzzi, Pierpaolo; Dominas, Christine; Fell, Geoffrey; Bernstock, Joshua D; Blitz, Sarah; Mazzetti, Debora; Zdioruk, Mykola; Dawood, Hassan Y; Triggs, Daniel V; Ahn, Sebastian W; Bhagavatula, Sharath K; Davidson, Shawn M; Tatarova, Zuzana; Pannell, Michael; Truman, Kyla; Ball, Anna; Gold, Maxwell P; Pister, Veronika; Fraenkel, Ernest; Chiocca, E Antonio; Ligon, Keith L; Wen, Patrick Y; Jonas, Oliver.
Affiliation
  • Peruzzi P; Department of Neurosurgery, Brigham and Women's Hospital, 60 Fenwood Road, Boston, MA 02115, USA.
  • Dominas C; Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Ave, Boston, MA 02115, USA.
  • Fell G; Department of Data Science, Dana Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA.
  • Bernstock JD; Department of Neurosurgery, Brigham and Women's Hospital, 60 Fenwood Road, Boston, MA 02115, USA.
  • Blitz S; Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA.
  • Mazzetti D; Department of Neurosurgery, Brigham and Women's Hospital, 60 Fenwood Road, Boston, MA 02115, USA.
  • Zdioruk M; Department of Neurosurgery, Brigham and Women's Hospital, 60 Fenwood Road, Boston, MA 02115, USA.
  • Dawood HY; Department of Neurosurgery, Brigham and Women's Hospital, 60 Fenwood Road, Boston, MA 02115, USA.
  • Triggs DV; Department of Neurosurgery, Brigham and Women's Hospital, 60 Fenwood Road, Boston, MA 02115, USA.
  • Ahn SW; Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Ave, Boston, MA 02115, USA.
  • Bhagavatula SK; Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Ave, Boston, MA 02115, USA.
  • Davidson SM; Lewis-Sigler Institute of Integrative Genomics, Princeton University, Princeton, NJ 08540, USA.
  • Tatarova Z; Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Ave, Boston, MA 02115, USA.
  • Pannell M; Department of Neurosurgery, Brigham and Women's Hospital, 60 Fenwood Road, Boston, MA 02115, USA.
  • Truman K; Department of Neurosurgery, Brigham and Women's Hospital, 60 Fenwood Road, Boston, MA 02115, USA.
  • Ball A; Department of Neurosurgery, Brigham and Women's Hospital, 60 Fenwood Road, Boston, MA 02115, USA.
  • Gold MP; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Pister V; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Fraenkel E; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Chiocca EA; Broad Institute of MIT and Harvard, Cambridge, MA 02139, USA.
  • Ligon KL; Department of Neurosurgery, Brigham and Women's Hospital, 60 Fenwood Road, Boston, MA 02115, USA.
  • Wen PY; Department of Pathology, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.
  • Jonas O; Division of Neuro-Oncology, Dana Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02115, USA.
Sci Transl Med ; 15(712): eadi0069, 2023 09 06.
Article de En | MEDLINE | ID: mdl-37672566

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Glioblastome / Gliome Type d'étude: Clinical_trials Limites: Humans Langue: En Journal: Sci Transl Med Sujet du journal: CIENCIA / MEDICINA Année: 2023 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: États-Unis d'Amérique

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Glioblastome / Gliome Type d'étude: Clinical_trials Limites: Humans Langue: En Journal: Sci Transl Med Sujet du journal: CIENCIA / MEDICINA Année: 2023 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: États-Unis d'Amérique