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Screening in serum-derived medium reveals differential response to compounds targeting metabolism.
Abbott, Keene L; Ali, Ahmed; Casalena, Dominick; Do, Brian T; Ferreira, Raphael; Cheah, Jaime H; Soule, Christian K; Deik, Amy; Kunchok, Tenzin; Schmidt, Daniel R; Renner, Steffen; Honeder, Sophie E; Wu, Michelle; Chan, Sze Ham; Tseyang, Tenzin; Stoltzfus, Andrew T; Michel, Sarah L J; Greaves, Daniel; Hsu, Peggy P; Ng, Christopher W; Zhang, Chelsea J; Farsidjani, Ali; Kent, Johnathan R; Madariaga, Maria Lucia L; Gramatikov, Iva Monique T; Matheson, Nicholas J; Lewis, Caroline A; Clish, Clary B; Rees, Matthew G; Roth, Jennifer A; Griner, Lesley Mathews; Muir, Alexander; Auld, Douglas S; Vander Heiden, Matthew G.
Affiliation
  • Abbott KL; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Ali A; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Casalena D; Novartis Institute for BioMedical Research, Cambridge, MA 02139, USA.
  • Do BT; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Harvard-MIT Health Sciences and Technology, Cambridge, MA 02139, USA.
  • Ferreira R; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.
  • Cheah JH; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Soule CK; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Deik A; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Kunchok T; Whitehead Institute for Biomedical Research, Cambridge, MA 02139, USA.
  • Schmidt DR; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Radiation Oncology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.
  • Renner S; Novartis Institutes for BioMedical Research, 4056 Basel, Switzerland.
  • Honeder SE; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Diagnostic and Research Institute of Pathology, Medical University of Graz, Graz, Austria.
  • Wu M; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Chan SH; Whitehead Institute for Biomedical Research, Cambridge, MA 02139, USA.
  • Tseyang T; Whitehead Institute for Biomedical Research, Cambridge, MA 02139, USA.
  • Stoltzfus AT; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, MD 21201, USA.
  • Michel SLJ; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, MD 21201, USA.
  • Greaves D; Cambridge Institute of Therapeutic Immunology & Infectious Disease, University of Cambridge, Cambridge CB2 0AW, UK; Department of Medicine, University of Cambridge, Cambridge CB2 0QQ, UK.
  • Hsu PP; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Dana-Farber Cancer Institute, Boston, MA 02115, USA; Massachusetts General Hospital Cancer Center, Boston, MA 02113, USA.
  • Ng CW; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Zhang CJ; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Farsidjani A; Novartis Institute for BioMedical Research, Cambridge, MA 02139, USA.
  • Kent JR; Department of Surgery, University of Chicago Medicine, Chicago, IL 60637, USA.
  • Madariaga MLL; Department of Surgery, University of Chicago Medicine, Chicago, IL 60637, USA.
  • Gramatikov IMT; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Radiation Oncology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.
  • Matheson NJ; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Cambridge Institute of Therapeutic Immunology & Infectious Disease, University of Cambridge, Cambridge CB2 0AW, UK; Department of Medicine, University of Cambridge, Cambridge CB2 0QQ,
  • Lewis CA; Whitehead Institute for Biomedical Research, Cambridge, MA 02139, USA.
  • Clish CB; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Rees MG; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Roth JA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Griner LM; Novartis Institute for BioMedical Research, Cambridge, MA 02139, USA.
  • Muir A; Ben May Department of Cancer Research, University of Chicago, Chicago, IL 60637, USA.
  • Auld DS; Novartis Institute for BioMedical Research, Cambridge, MA 02139, USA.
  • Vander Heiden MG; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Dana-Farber Cancer Institute, Boston,
Cell Chem Biol ; 30(9): 1156-1168.e7, 2023 09 21.
Article de En | MEDLINE | ID: mdl-37689063
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Techniques de culture cellulaire / Tests de criblage à haut débit Type d'étude: Diagnostic_studies / Prognostic_studies / Screening_studies Limites: Humans Langue: En Journal: Cell Chem Biol Année: 2023 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: États-Unis d'Amérique
Texte intégral
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Techniques de culture cellulaire / Tests de criblage à haut débit Type d'étude: Diagnostic_studies / Prognostic_studies / Screening_studies Limites: Humans Langue: En Journal: Cell Chem Biol Année: 2023 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: États-Unis d'Amérique