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First Potent Macrocyclic A3 Adenosine Receptor Agonists Reveal G-Protein and ß-Arrestin2 Signaling Preferences.
Tosh, Dilip K; Fisher, Courtney L; Salmaso, Veronica; Wan, Tina C; Campbell, Ryan G; Chen, Eric; Gao, Zhan-Guo; Auchampach, John A; Jacobson, Kenneth A.
Affiliation
  • Tosh DK; Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Disease, National Institutes of Health, 9000 Rockville Pike, Bethesda, Maryland 20892, United States.
  • Fisher CL; Department of Pharmacology & Toxicology and the Cardiovascular Center, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, Wisconsin 53226, United States.
  • Salmaso V; Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Disease, National Institutes of Health, 9000 Rockville Pike, Bethesda, Maryland 20892, United States.
  • Wan TC; Molecular Modeling Section, Department of Pharmaceutical and Pharmacological Sciences, University of Padua, Padua 35131, Italy.
  • Campbell RG; Department of Pharmacology & Toxicology and the Cardiovascular Center, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, Wisconsin 53226, United States.
  • Chen E; Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Disease, National Institutes of Health, 9000 Rockville Pike, Bethesda, Maryland 20892, United States.
  • Gao ZG; Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Disease, National Institutes of Health, 9000 Rockville Pike, Bethesda, Maryland 20892, United States.
  • Auchampach JA; Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Disease, National Institutes of Health, 9000 Rockville Pike, Bethesda, Maryland 20892, United States.
  • Jacobson KA; Department of Pharmacology & Toxicology and the Cardiovascular Center, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, Wisconsin 53226, United States.
ACS Pharmacol Transl Sci ; 6(9): 1288-1305, 2023 Sep 08.
Article de En | MEDLINE | ID: mdl-37705595

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Aspects: Patient_preference Langue: En Journal: ACS Pharmacol Transl Sci Année: 2023 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: États-Unis d'Amérique

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Aspects: Patient_preference Langue: En Journal: ACS Pharmacol Transl Sci Année: 2023 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: États-Unis d'Amérique