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N4-hydroxycytidine, the active compound of Molnupiravir, promotes SARS-CoV-2 mutagenesis and escape from a neutralizing nanobody.
Zibat, Arne; Zhang, Xiaoxiao; Dickmanns, Antje; Stegmann, Kim M; Dobbelstein, Adrian W; Alachram, Halima; Soliwoda, Rebecca; Salinas, Gabriela; Groß, Uwe; Görlich, Dirk; Kschischo, Maik; Wollnik, Bernd; Dobbelstein, Matthias.
Affiliation
  • Zibat A; Department of Human Genetics, University Medical Center Göttingen, 37073 Göttingen, Germany.
  • Zhang X; Department of Mathematics and Technology, University of Applied Sciences Koblenz, 53424 Remagen, Germany.
  • Dickmanns A; Department of Informatics, Technical University of Munich, 81675 Munich, Germany.
  • Stegmann KM; Department of Molecular Oncology, Göttingen Center of Molecular Biosciences (GZMB), University Medical Center Göttingen, 37077 Göttingen, Germany.
  • Dobbelstein AW; Department of Molecular Oncology, Göttingen Center of Molecular Biosciences (GZMB), University Medical Center Göttingen, 37077 Göttingen, Germany.
  • Alachram H; Max Planck Institute for Biology, 72076 Tübingen, Germany.
  • Soliwoda R; Department of Human Genetics, University Medical Center Göttingen, 37073 Göttingen, Germany.
  • Salinas G; Department of Molecular Oncology, Göttingen Center of Molecular Biosciences (GZMB), University Medical Center Göttingen, 37077 Göttingen, Germany.
  • Groß U; NGS Integrative Genomics Core Unit, Department of Human Genetics, University Medical Center Göttingen, 37077 Göttingen, Germany.
  • Görlich D; Department of Medical Microbiology and Virology, University Medical Center Göttingen, 37075 Göttingen, Germany.
  • Kschischo M; Max Planck Institute for Multidisciplinary Sciences, 37077 Göttingen, Germany.
  • Wollnik B; Department of Mathematics and Technology, University of Applied Sciences Koblenz, 53424 Remagen, Germany.
  • Dobbelstein M; Department of Human Genetics, University Medical Center Göttingen, 37073 Göttingen, Germany.
iScience ; 26(10): 107786, 2023 Oct 20.
Article de En | MEDLINE | ID: mdl-37731621
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Langue: En Journal: IScience Année: 2023 Type de document: Article Pays d'affiliation: Allemagne Pays de publication: États-Unis d'Amérique
Texte intégral
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Langue: En Journal: IScience Année: 2023 Type de document: Article Pays d'affiliation: Allemagne Pays de publication: États-Unis d'Amérique