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ASPP2 binds to hepatitis C virus NS5A protein via an SH3 domain/PxxP motif-mediated interaction and potentiates infection.
Smirnov, Artem; Magri, Andrea; Lotz, Rebecca; Han, Xiaoyue; Yin, Chunhong; Harris, Mark; Osterburg, Christian; Dötsch, Volker; McKeating, Jane A; Lu, Xin.
Affiliation
  • Smirnov A; Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford OX3 7DQ, UK.
  • Magri A; Department of Experimental Medicine, TOR, University of Rome "Tor Vergata", Rome 00133, Italy.
  • Lotz R; Nuffield Department of Clinical Medicine, University of Oxford, Oxford OX3 7FZ, UK.
  • Han X; Institute of Biophysical Chemistry and Center for Biomolecular Magnetic Resonance, Goethe University, Frankfurt, Germany.
  • Yin C; Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford OX3 7DQ, UK.
  • Harris M; School of Molecular and Cellular Biology, Faculty of Biological Sciences, and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, UK.
  • Osterburg C; Present address: State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, PR China.
  • Dötsch V; School of Molecular and Cellular Biology, Faculty of Biological Sciences, and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, UK.
  • McKeating JA; Institute of Biophysical Chemistry and Center for Biomolecular Magnetic Resonance, Goethe University, Frankfurt, Germany.
  • Lu X; Institute of Biophysical Chemistry and Center for Biomolecular Magnetic Resonance, Goethe University, Frankfurt, Germany.
J Gen Virol ; 104(9)2023 09.
Article de En | MEDLINE | ID: mdl-37750869

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Hépatite C / Hepacivirus Type d'étude: Prognostic_studies Limites: Humans Langue: En Journal: J Gen Virol Année: 2023 Type de document: Article Pays d'affiliation: Royaume-Uni Pays de publication: Royaume-Uni

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Hépatite C / Hepacivirus Type d'étude: Prognostic_studies Limites: Humans Langue: En Journal: J Gen Virol Année: 2023 Type de document: Article Pays d'affiliation: Royaume-Uni Pays de publication: Royaume-Uni