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Enhanced broad spectrum in vitro antiviral efficacy of 3-F-4-MeO-Bn, 3-CN, and 4-CN derivatives of lipid remdesivir nucleoside monophosphate prodrugs.
McMillan, Rachel E; Lo, Michael K; Zhang, Xing-Quan; Beadle, James R; Valiaeva, Nadejda; Garretson, Aaron F; Clark, Alex E; Freshman, Jon E; Murphy, Joyce; Montgomery, Joel M; Spiropoulou, Christina F; Schooley, Robert T; Hostetler, Karl Y; Carlin, Aaron F.
Affiliation
  • McMillan RE; Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego, School of Medicine, La Jolla, CA, USA; Department of Pathology, University of California San Diego, School of Medicine, La Jolla, CA, USA.
  • Lo MK; Viral Special Pathogens Branch, Centers for Disease Control and Prevention, Department of Health and Human Services, Atlanta, CA, USA.
  • Zhang XQ; Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego, School of Medicine, La Jolla, CA, USA.
  • Beadle JR; Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego, School of Medicine, La Jolla, CA, USA.
  • Valiaeva N; Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego, School of Medicine, La Jolla, CA, USA.
  • Garretson AF; Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego, School of Medicine, La Jolla, CA, USA; Department of Pathology, University of California San Diego, School of Medicine, La Jolla, CA, USA.
  • Clark AE; Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego, School of Medicine, La Jolla, CA, USA; Department of Pathology, University of California San Diego, School of Medicine, La Jolla, CA, USA.
  • Freshman JE; Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego, School of Medicine, La Jolla, CA, USA; Department of Pathology, University of California San Diego, School of Medicine, La Jolla, CA, USA.
  • Murphy J; Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego, School of Medicine, La Jolla, CA, USA.
  • Montgomery JM; Viral Special Pathogens Branch, Centers for Disease Control and Prevention, Department of Health and Human Services, Atlanta, CA, USA.
  • Spiropoulou CF; Viral Special Pathogens Branch, Centers for Disease Control and Prevention, Department of Health and Human Services, Atlanta, CA, USA.
  • Schooley RT; Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego, School of Medicine, La Jolla, CA, USA.
  • Hostetler KY; Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego, School of Medicine, La Jolla, CA, USA.
  • Carlin AF; Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego, School of Medicine, La Jolla, CA, USA; Department of Pathology, University of California San Diego, School of Medicine, La Jolla, CA, USA. Electronic address: acarlin@health.ucsd.edu
Antiviral Res ; 219: 105718, 2023 11.
Article de En | MEDLINE | ID: mdl-37758067

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Antiviraux / Promédicaments Langue: En Journal: Antiviral Res Année: 2023 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: Pays-Bas

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Antiviraux / Promédicaments Langue: En Journal: Antiviral Res Année: 2023 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: Pays-Bas