Inhibitory mechanism of vortioxetine on CYP450 enzymes in human and rat liver microsomes.

Zhan, Yunyun; Wang, Anzhou; Yu, Yige; Chen, Jie; Xu, Xinhao; Nie, Jingjing; Lin, Jingjing

Zhan, Yunyun; Wang, Anzhou; Yu, Yige; Chen, Jie; Xu, Xinhao; Nie, Jingjing; Lin, Jingjing.

Affiliation

Zhan Y; Department of Pharmacy, The Affiliated Lihuili Hospital, Ningbo University, Ningbo, Zhejiang, China.
Wang A; Department of Pharmacy, The Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Yu Y; Department of Pharmacy, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Chen J; Department of Pharmacy, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Xu X; Department of Pharmacy, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Nie J; Department of Pharmacy, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Lin J; Department of Pharmacy, The Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.

Front Pharmacol ; 14: 1199548, 2023.

Article de En | MEDLINE | ID: mdl-37790811

Mots clés

CYP450; UPLC-MS/MS; drug-drug interaction; inhibition mechanism; vortioxetine

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Type d'étude: Guideline Langue: En Journal: Front Pharmacol Année: 2023 Type de document: Article Pays d'affiliation: Chine Pays de publication: Suisse

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