[Relation factor analysis for the short-term preservation of ipsilateral renal function after partial nephrectomy].
Zhonghua Wai Ke Za Zhi
; 61(12): 1099-1103, 2023 Dec 01.
Article
de Zh
| MEDLINE
| ID: mdl-37932147
ABSTRACT
Objectives:
To analyze the factors relative to the short-term preservation of ipsilateral renal function after partial nephrectomy.Methods:
The clinical data of 83 patients who were treated with partial nephrectomy from December 2014 to December 2019 in the Department of Urology, Sun Yat-sen University Cancer Center were retrospectively analyzed. There were 54 males and 29 females, aging (M (IQR)) 49 (17) years (range 27 to 74 years). The ischemia time in operation was 25 (18) minutes (range 10 to 67 minutes). Emission computed tomography scan and CT scan were performed before (within 1 month) and after (3 to 12 months) surgery. The volume of the ipsilateral and contralateral kidney was measured on the basis of preoperative and postoperative CT scans. The glomerular filtration rate (GFR) specifically in each kidney was estimated by emission computed tomography. Recovery from ischemia is determined by the formula GFR preservation/volume saved×100%. Linear regression was used to explore the factors ralative to the short-term preservation of ipsilateral renal function after partial nephrectomy.Results:
The GFR preservation of the ipsilateral kidney was 80.9 (25.2) % (range 31.0% to 109.4%). The volume loss of the kidney resulted in a decrease of 12.0% (5.8 ml/(min×1.96 m2)) of GFR, while the ischemic injury resulted in a decrease of 6.5% (2.5 ml/(min×1.96 m2)) of GFR. The volume saved from the ipsilateral kidney was 87.1 (12.9) % (range 27.0% to 131.7%). Recovery from ischemia was 93.5 (17.5) % (range44.3% to 178.3%). In multivariate analysis, GFR preservation of the ipsilateral kidney was significantly correlated with the volume saved of the ipsilateral kidney (ß=0.383, 95%CI 0.144 to 0.622, P=0.002). It was not related to the ischemia time (ß=0.046, 95%CI-0.383 to 0.475, P=0.831).Conclusion:
In the condition of limited ischemic time, in the short term ipsilateral renal function after partial nephrectomy is mainly determined by the loss of kidney volume, while ischemic injury only plays a minor role.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Tumeurs du rein
Limites:
Female
/
Humans
/
Male
Langue:
Zh
Journal:
Zhonghua Wai Ke Za Zhi
Année:
2023
Type de document:
Article
Pays d'affiliation:
Chine