Anti-inflammatory and analgesic properties of Polyphyllin VI revealed by network pharmacology and RNA sequencing.

Zhang, Zhenglang; Wang, Tingting; Luo, Zhenhui; Zaib, Muhammad Haris; Yi, Mengqin; Zeng, Hekun; Li, Peiyang; Tang, Dan; Verkhratsky, Alexei; Nie, Hong

Zhang, Zhenglang; Wang, Tingting; Luo, Zhenhui; Zaib, Muhammad Haris; Yi, Mengqin; Zeng, Hekun; Li, Peiyang; Tang, Dan; Verkhratsky, Alexei; Nie, Hong.

Affiliation

Zhang Z; State Key Laboratory of Bioactive Molecules and Druggability Assessment, Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Mini
Wang T; State Key Laboratory of Bioactive Molecules and Druggability Assessment, Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Mini
Luo Z; State Key Laboratory of Bioactive Molecules and Druggability Assessment, Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Mini
Zaib MH; State Key Laboratory of Bioactive Molecules and Druggability Assessment, Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Mini
Yi M; State Key Laboratory of Bioactive Molecules and Druggability Assessment, Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Mini
Zeng H; State Key Laboratory of Bioactive Molecules and Druggability Assessment, Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Mini
Li P; State Key Laboratory of Bioactive Molecules and Druggability Assessment, Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Mini
Tang D; Key Laboratory of Digital Quality Evaluation of Chinese Materia Medica of State Administration of TCM and Engineering & Technology Research Center for Chinese Materia Medica Quality of Guangdong Province, Guangdong Pharmaceutical University, Guangzhou, 510006, China.
Verkhratsky A; Faculty of Biology, Medicine, and Health, the University of Manchester, Manchester, UK. alexej.verkhratsky@manchester.ac.uk.
Nie H; State Key Laboratory of Bioactive Molecules and Druggability Assessment, Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Mini

Purinergic Signal ; 2023 Nov 20.

Article de En | MEDLINE | ID: mdl-37981630

Mots clés

Inflammatory pain; Network pharmacology; P2X7 receptor; Polyphyllin VI; RNA sequencing

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Langue: En Journal: Purinergic Signal Année: 2023 Type de document: Article