A novel complement-fixing IgM antibody targeting GPC1 as a useful immunotherapeutic strategy for the treatment of pancreatic ductal adenocarcinoma.

Busato, Davide; Capolla, Sara; Durigutto, Paolo; Mossenta, Monica; Bozzer, Sara; Sblattero, Daniele; Macor, Paolo; Dal Bo, Michele; Toffoli, Giuseppe

Busato, Davide; Capolla, Sara; Durigutto, Paolo; Mossenta, Monica; Bozzer, Sara; Sblattero, Daniele; Macor, Paolo; Dal Bo, Michele; Toffoli, Giuseppe.

Affiliation

Busato D; Experimental and Clinical Pharmacology, Centro Di Riferimento Oncologico (CRO) Di Aviano IRCCS, 33081, Aviano, Italy.
Capolla S; Department of Life Sciences, University of Trieste, 34127, Trieste, Italy.
Durigutto P; Experimental and Clinical Pharmacology, Centro Di Riferimento Oncologico (CRO) Di Aviano IRCCS, 33081, Aviano, Italy.
Mossenta M; Department of Life Sciences, University of Trieste, 34127, Trieste, Italy.
Bozzer S; Experimental and Clinical Pharmacology, Centro Di Riferimento Oncologico (CRO) Di Aviano IRCCS, 33081, Aviano, Italy.
Sblattero D; Department of Life Sciences, University of Trieste, 34127, Trieste, Italy.
Macor P; Experimental and Clinical Pharmacology, Centro Di Riferimento Oncologico (CRO) Di Aviano IRCCS, 33081, Aviano, Italy.
Dal Bo M; Department of Life Sciences, University of Trieste, 34127, Trieste, Italy.
Toffoli G; Department of Life Sciences, University of Trieste, 34127, Trieste, Italy.

J Transl Med ; 21(1): 864, 2023 11 28.

Article de En | MEDLINE | ID: mdl-38017492

Sujet(s)
Mots clés

Complement System; GPC1; IgM; Immunotherapy; PDAC

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Tumeurs du pancréas / Carcinome du canal pancréatique Limites: Adult / Animals / Humans Langue: En Journal: J Transl Med Année: 2023 Type de document: Article Pays d'affiliation: Italie

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