Structural basis of a redox-dependent conformational switch that regulates the stress kinase p38&#945;.

Pous, Joan; Baginski, Blazej; Martin-Malpartida, Pau; González, Lorena; Scarpa, Margherita; Aragon, Eric; Ruiz, Lidia; Mees, Rebeca A; Iglesias-Fernández, Javier; Orozco, Modesto; Nebreda, Angel R; Macias, Maria J

Structural basis of a redox-dependent conformational switch that regulates the stress kinase p38α.

Pous, Joan; Baginski, Blazej; Martin-Malpartida, Pau; González, Lorena; Scarpa, Margherita; Aragon, Eric; Ruiz, Lidia; Mees, Rebeca A; Iglesias-Fernández, Javier; Orozco, Modesto; Nebreda, Angel R; Macias, Maria J.

Affiliation

Pous J; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri Reixac, 10, 08028, Barcelona, Spain.
Baginski B; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri Reixac, 10, 08028, Barcelona, Spain.
Martin-Malpartida P; Global Health Medicines R&D, GSK, c/ Severo Ochoa, 2, 28760, Tres Cantos, Madrid, Spain.
González L; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri Reixac, 10, 08028, Barcelona, Spain.
Scarpa M; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri Reixac, 10, 08028, Barcelona, Spain.
Aragon E; Grupo Menarini España, c/ d'Alfons XII, 587, 08918, Badalona, Barcelona, Spain.
Ruiz L; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri Reixac, 10, 08028, Barcelona, Spain.
Mees RA; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri Reixac, 10, 08028, Barcelona, Spain.
Iglesias-Fernández J; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri Reixac, 10, 08028, Barcelona, Spain.
Orozco M; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri Reixac, 10, 08028, Barcelona, Spain.
Nebreda AR; Nostrum Biodiscovery, Josep Tarradellas 8-10, 3-2, 08029, Barcelona, Spain.
Macias MJ; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri Reixac, 10, 08028, Barcelona, Spain.

Nat Commun ; 14(1): 7920, 2023 Dec 01.

Article de En | MEDLINE | ID: mdl-38040726

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Mitogen-Activated Protein Kinase 14 Limites: Animals Langue: En Journal: Nat Commun Sujet du journal: BIOLOGIA / CIENCIA Année: 2023 Type de document: Article Pays d'affiliation: Espagne Pays de publication: Royaume-Uni

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