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Exploring the effects of experimental parameters and data modeling approaches on in vitro transcriptomic point-of-departure estimates.
Harrill, Joshua A; Everett, Logan J; Haggard, Derik E; Bundy, Joseph L; Willis, Clinton M; Shah, Imran; Friedman, Katie Paul; Basili, Danilo; Middleton, Alistair; Judson, Richard S.
Affiliation
  • Harrill JA; Center for Computational Toxicology and Exposure, Office of Research and Development, US Environmental Protection Agency, Research Triangle Park, NC, USA.
  • Everett LJ; Center for Computational Toxicology and Exposure, Office of Research and Development, US Environmental Protection Agency, Research Triangle Park, NC, USA.
  • Haggard DE; Center for Computational Toxicology and Exposure, Office of Research and Development, US Environmental Protection Agency, Research Triangle Park, NC, USA; Oak Ridge Institute for Science and Education (ORISE), USA.
  • Bundy JL; Center for Computational Toxicology and Exposure, Office of Research and Development, US Environmental Protection Agency, Research Triangle Park, NC, USA.
  • Willis CM; Center for Computational Toxicology and Exposure, Office of Research and Development, US Environmental Protection Agency, Research Triangle Park, NC, USA; Oak Ridge Associated Universities (ORAU), USA.
  • Shah I; Center for Computational Toxicology and Exposure, Office of Research and Development, US Environmental Protection Agency, Research Triangle Park, NC, USA.
  • Friedman KP; Center for Computational Toxicology and Exposure, Office of Research and Development, US Environmental Protection Agency, Research Triangle Park, NC, USA.
  • Basili D; Unilever Safety and Environmental Assurance Centre (SEAC), Colworth Science Park, Sharnbrook, Bedfordshire MK44 1LQ, UK.
  • Middleton A; Unilever Safety and Environmental Assurance Centre (SEAC), Colworth Science Park, Sharnbrook, Bedfordshire MK44 1LQ, UK.
  • Judson RS; Center for Computational Toxicology and Exposure, Office of Research and Development, US Environmental Protection Agency, Research Triangle Park, NC, USA. Electronic address: judson.richard@epa.gov.
Toxicology ; 501: 153694, 2024 01.
Article de En | MEDLINE | ID: mdl-38043774

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Analyse de profil d'expression de gènes / Transcriptome Limites: Humans Langue: En Journal: Toxicology Année: 2024 Type de document: Article Pays d'affiliation: États-Unis d'Amérique

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Analyse de profil d'expression de gènes / Transcriptome Limites: Humans Langue: En Journal: Toxicology Année: 2024 Type de document: Article Pays d'affiliation: États-Unis d'Amérique