Is CaMKII friend or foe for cell apoptosis in eye?: A narrative review.
Medicine (Baltimore)
; 102(48): e36136, 2023 Dec 01.
Article
de En
| MEDLINE
| ID: mdl-38050317
ABSTRACT
Ca2+/calmodulin-dependent protein kinase II (CaMKII) controls cell proliferation, differentiation, apoptosis, and other biological processes that have an essential role in eye diseases. However, it seems that previous studies have generated conflicting conclusions about the effect of CaMKII on cell apoptosis. In this review, we explore the positive and potentially deleterious effects of CaMKII on eye cell apoptosis. We can safely conclude that the early elevation of CaMKII could be viewed as a promoter of cell apoptosis. Overexpression of CaMKII by transfection or pretreatment with drugs helped combat cell apoptosis.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Apoptose
/
Calcium-Calmodulin-Dependent Protein Kinase Type 2
Limites:
Humans
Langue:
En
Journal:
Medicine (Baltimore)
Année:
2023
Type de document:
Article
Pays d'affiliation:
Chine