Development of a fumonisin-sensitive Saccharomyces cerevisiae indicator strain and utilization for activity testing of candidate detoxification genes.
Appl Environ Microbiol
; 89(12): e0121123, 2023 12 21.
Article
de En
| MEDLINE
| ID: mdl-38054733
ABSTRACT
IMPORTANCE Fumonisins can cause diseases in animals and humans consuming Fusarium-contaminated food or feed. The search for microbes capable of fumonisin degradation, or for enzymes that can detoxify fumonisins, currently relies primarily on chemical detection methods. Our constructed fumonisin B1-sensitive yeast strain can be used to phenotypically detect detoxification activity and should be useful in screening for novel fumonisin resistance genes and to elucidate fumonisin metabolism and resistance mechanisms in fungi and plants, and thereby, in the long term, help to mitigate the threat of fumonisins in feed and food.
Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Fumonisines
/
Fusarium
Limites:
Animals
/
Humans
Langue:
En
Journal:
Appl Environ Microbiol
Année:
2023
Type de document:
Article
Pays d'affiliation:
Autriche