Gnathic Schwannomas: A Report of Two Cases and Systematic Review of the Literature.
Head Neck Pathol
; 17(4): 984-999, 2023 Dec.
Article
de En
| MEDLINE
| ID: mdl-38055108
ABSTRACT
BACKGROUND:
The intraosseous schwannoma (IS) is a benign peripheral nerve sheath tumor postulated to arise de novo or from nerve fibers in preexisting nutrient canals. ISs are uncommon and comprise less than 1% of neoplasms originating in bone. We herein present two cases of mandibular schwannomas-the first case was a 66-year-old female with a four-month history of pain and pressure associated with an anterior mandibular radiolucency, and the second case was an asymptomatic 12-year-old female with separate radiolucencies of her mandibular symphysis and right posterior mandible. Incisional biopsies of all three lesions showed a benign spindle cell neoplasm with histologic features of a schwannoma; the tumor cells were strongly reactive for S-100. The patients underwent complete enucleation of their lesions and are without evidence of disease at ten months and five years, respectively.METHODS:
A systematic review was undertaken to evaluate the diagnostic features, treatment, and patient outcomes of gnathic schwannomas.RESULTS:
A total of 93 cases were identified with the following demographicfindings:
predominance in females (57%); average age of occurrence of 37.3 years (8 to 77 years); mean size of 3.6 cm; and involvement of the mandibular body (37.6%), mandibular body and ramus (18.3%), and anterior mandible (18.3%). The predominant clinical sign was swelling (69.9%), and the most common radiographic presentation was a radiolucency (94.6%) with well-defined borders (72%).CONCLUSION:
All cases were treated surgically, with an average follow-up interval of 22.9 months and a recurrence rate of 5.4.Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Neurinome
Type d'étude:
Systematic_reviews
Limites:
Adult
/
Aged
/
Child
/
Female
/
Humans
Langue:
En
Journal:
Head Neck Pathol
Sujet du journal:
NEOPLASIAS
/
PATOLOGIA
Année:
2023
Type de document:
Article
Pays d'affiliation:
États-Unis d'Amérique