Characteristics of Chryseobacterium bacteremia, associated risk factors and their antibiotic susceptibility pattern at a university hospital: a descriptive, retrospective study.
Access Microbiol
; 5(11)2023.
Article
de En
| MEDLINE
| ID: mdl-38074110
ABSTRACT
Introduction:
Chryseobacterium species are emerging bacteria capable of causing nosocomial infections in immunocompromised patients or patients with indwelling medical devices. Hypothesis/ Gap statement Information about the incidence of Chryseobacterium bacteremia from worldwide literature is limited.Aim:
We aimed to recognize the clinical characteristics, frequency of distribution of different Chryseobacterium species isolates, and their antimicrobial susceptibility profile from bloodstream infections.Methods:
We performed a retrospective cohort study to identify all isolates of Chryseobacterium species from bloodstream infection from January 2018 to November 2022 at a university hospital in North India.Results:
We identified 42 non-duplicate isolates of Chryseobacterium species from bloodstream infection in the duration of our study. Mean age of the patients was 48.35±16.63 years. Men (22/42, 52.2â%) were more commonly affected in comparison to women (20/42, 47.6â%) but the difference was not significant. The most common species identified was C. indologenes (40/42, 95.24â%) followed by C. gleum (2/42, 4.76â%). The co-morbidities commonly encountered in our study were chronic kidney disease (21/42, 50.0â%) followed by diabetes mellitus (12/42, 28.6â%) and chronic obstructive pulmonary disease (8/42, 19.05â%). All patients had intravenous access to medications or fluid management via a central or peripheral line and mechanical ventilation was observed in 39 (39/42, 92.86â%) patients. All the isolates were susceptible to minocycline (100â%), followed by doxycycline (97.6â%) and trimethoprim-sulfamethoxazole (95.2â%).Conclusion:
Chryseobacterium species are capable of causing pneumonia, bacteremia and urinary tract infection in immunocompromised patients. Early diagnosis and prompt treatment with appropriate antibiotics can prevent progression to septicemia.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Langue:
En
Journal:
Access Microbiol
Année:
2023
Type de document:
Article
Pays d'affiliation:
Inde