Mesoaccumbal glutamate neurons drive reward via glutamate release but aversion via dopamine co-release.

Warlow, Shelley M; Singhal, Sarthak M; Hollon, Nick G; Faget, Lauren; Dowlat, Dina S; Zell, Vivien; Hunker, Avery C; Zweifel, Larry S; Hnasko, Thomas S

Warlow, Shelley M; Singhal, Sarthak M; Hollon, Nick G; Faget, Lauren; Dowlat, Dina S; Zell, Vivien; Hunker, Avery C; Zweifel, Larry S; Hnasko, Thomas S.

Affiliation

Warlow SM; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
Singhal SM; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
Hollon NG; Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA.
Faget L; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
Dowlat DS; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
Zell V; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
Hunker AC; Department of Pharmacology, University of Washington, Seattle, WA, USA.
Zweifel LS; Department of Pharmacology, University of Washington, Seattle, WA, USA.
Hnasko TS; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA; Veterans Affairs San Diego Healthcare System, San Diego, CA, USA. Electronic address: thnasko@health.ucsd.edu.

Neuron ; 112(3): 488-499.e5, 2024 Feb 07.

Article de En | MEDLINE | ID: mdl-38086374

Sujet(s)
Mots clés

CRISPR-Cas9; VGLUT2; dopamine; glutamate; reinforcement; reward; ventral tegmental area

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Dopamine / Acide glutamique Limites: Animals Langue: En Journal: Neuron Sujet du journal: NEUROLOGIA Année: 2024 Type de document: Article Pays d'affiliation: États-Unis d'Amérique

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