APOE3ch alters microglial response and suppresses Aß-induced tau seeding and spread.

Chen, Yun; Song, Sihui; Parhizkar, Samira; Lord, Jennifer; Zhu, Yiyang; Strickland, Michael R; Wang, Chanung; Park, Jiyu; Tabor, G Travis; Jiang, Hong; Li, Kevin; Davis, Albert A; Yuede, Carla M; Colonna, Marco; Ulrich, Jason D; Holtzman, David M

Chen, Yun; Song, Sihui; Parhizkar, Samira; Lord, Jennifer; Zhu, Yiyang; Strickland, Michael R; Wang, Chanung; Park, Jiyu; Tabor, G Travis; Jiang, Hong; Li, Kevin; Davis, Albert A; Yuede, Carla M; Colonna, Marco; Ulrich, Jason D; Holtzman, David M.

Affiliation

Chen Y; Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Song S; Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Parhizkar S; Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO
Lord J; Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Zhu Y; Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Strickland MR; Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Wang C; Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Park J; Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Tabor GT; Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Jiang H; Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO
Li K; Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Davis AA; Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA.
Yuede CM; Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO
Colonna M; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA.
Ulrich JD; Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO
Holtzman DM; Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO

Cell ; 187(2): 428-445.e20, 2024 01 18.

Article de En | MEDLINE | ID: mdl-38086389

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Peptides bêta-amyloïdes / Protéines tau / Apolipoprotéine E3 / Maladie d'Alzheimer Limites: Animals / Humans Langue: En Journal: Cell Année: 2024 Type de document: Article Pays d'affiliation: États-Unis d'Amérique

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