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Successful treatment of classic Kaposi sarcoma with Trichophyton rubrum-infected onychomycosis and tinea pedis utilizing combination of oral itraconazole and thalidomide.
Chen, Jincong; Zheng, Yaxuan; Zhu, Changhua; Lin, Lihang; Su, Huichun.
Affiliation
  • Chen J; Department of Dermatology, Fujian Medical University Union Hospital, Fuzhou, China.
  • Zheng Y; Department of Dermatology, Fujian Medical University Union Hospital, Fuzhou, China.
  • Zhu C; Department of Dermatology, Fujian Medical University Union Hospital, Fuzhou, China.
  • Lin L; Department of Dermatology, Fujian Medical University Union Hospital, Fuzhou, China.
  • Su H; Department of Dermatology, Fujian Medical University Union Hospital, Fuzhou, China.
J Dermatol ; 2023 Dec 12.
Article de En | MEDLINE | ID: mdl-38087640
Kaposi sarcoma (KS) is a vascular proliferative tumor caused by human herpesvirus 8. At present, the treatment of KS is difficult and refractory. Here, we report a 68-year-old man who was diagnosed with a classical KS with tinea pedis and onychomycosis, infected by Trichophyton rubrum, and treated with itraconazole and thalidomide after locational excision of several bigger nodules. The lesions were relieved during treatment, and recurred after discontinuation. Retreatment still achieved good effect and the therapy was tapered down after control. After the whole course of treatment, the skin lesions subsided significantly without obvious adverse reactions, which showed that itraconazole combined with thalidomide may be another effective and safe treatment for KS in some cases.
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Langue: En Journal: J Dermatol Année: 2023 Type de document: Article Pays d'affiliation: Chine Pays de publication: Royaume-Uni

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Langue: En Journal: J Dermatol Année: 2023 Type de document: Article Pays d'affiliation: Chine Pays de publication: Royaume-Uni