Vivax malaria and Duffy antigen: Stop being so negative.

Duffy, Patrick E; Gunalan, Karthigayan; Miller, Louis H

Duffy, Patrick E; Gunalan, Karthigayan; Miller, Louis H.

Affiliation

Duffy PE; Laboratory of Malaria Immunology and Vaccinology, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, USA. Electronic address: patrick.duffy@nih.gov.
Gunalan K; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, NIH, Rockville, MD, USA.
Miller LH; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, NIH, Rockville, MD, USA.

Cell Host Microbe ; 31(12): 1959-1960, 2023 Dec 13.

Article de En | MEDLINE | ID: mdl-38096790

ABSTRACT

ABSTRACT

Duffy blood group antigen (Duffy antigen/receptor for chemokines, atypical chemokine receptor-1, Duffy antigen), an essential Plasmodium vivax invasion receptor, is absent in most Africans. In this issue, two papers show erythroid precursors from Duffy-negative individuals transiently surface-express Duffy antigen and support vivax infection, potentially explaining low-density vivax infections across Africa.

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Paludisme à Plasmodium vivax Limites: Humans Langue: En Journal: Cell Host Microbe Sujet du journal: MICROBIOLOGIA Année: 2023 Type de document: Article

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